Connor O'Leary
@connorjolearyChemical biology PhD Researcher @McGouranGroup @tcddublin. MChem @DurhamChemistry. #FBPE
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Thrilled to see our first contribution out in @J_A_C_S! @uaitaciano, Roberto, Órla & Ben developed a practical, broad-scope and selective strategy for alkene 1,2-syn-difunctionalization, combining 1,3-DCs with electrochemical radical activation🪡✂️ 📜🔗:pubs.acs.org/doi/10.1021/ja…
Paper #7 of 2024. Happy to finally publish this. In 2019 I tasked new PhD student @Samantha_Bann with a new synthesis of globomycin. This is a project that did not go to plan and Sam showed great resilience and dedication to get it over the line! pubs.rsc.org/en/content/art…
Many congrats to @PaschkeAK, @Yannickbraegger, @BenceBBotlik, Erich and @origree1 - Carbon-to-nitrogen atom swap enables direct access to benzimidazoles from drug-like indoles @ChemRxiv go.shr.lc/3BLpk8u
Are you looking for a PhD position in peptide synthesis, automation, and computational analysis? 🧪 💊💻 We have an open position for a collaborative PhD thesis (with Novo Nordisk). For more details, please see: jobs.uzh.ch/job-vacancies/… ⏰ Application deadline = November 15
Keir Starmer has made strides, but his reluctance on youth mobility is a missed opportunity. We must prioritise young people’s futures over optics and seize this opportunity to build bridges with Europe and within the UK. Let’s not waste it. bit.ly/4ePVptU
Recently, we posted a preprint on a novel strategy on stereospecific C-glycosylation via formal functional group deletion. A broad scope of heterocycles can be installed at the anomeric position stereospecifically. Check it out! @ChemRxiv #MerckChemistry go.shr.lc/3ZNYJl4
Proud #newPI moment to share the first @J_A_C_S paper from my independent group @ChemistryUoN on structural transformations of Pd metal-organic cages with work done by group members @Mrb_Black and @09Soumalya and help from @steppphhhen pubs.acs.org/doi/10.1021/ja…
The Economist has absolutely smashed it out of the park with this article. A classic Economist analysis piece, clipped style, but not being said elsewhere. A 🧵
Applications for the EMBL International PhD Programme are open! 👀 The programme offers fully funded PhD positions at EMBL’s six sites across Europe 🌍 Have a look at this opportunity to start your career in the life sciences here: embl.org/about/info/emb…
Great to see our work out this week in JACS @kaydanych @Prevedel_Lab @claire_deo Hopefully just the start of a wave of photoacoustic probe development to complement existing neuroimaging tools! pubs.acs.org/doi/10.1021/ja…
This is just out from our lab, a tutorial review on Small Lectin Ligands as a Basis for Applications in Glycoscience and Glycomedicine. doi.org/10.1039/D4CS00…
How to: chromatography using a pipette chem.rochester.edu/notvoodoo/page… guide sent in by @valentin_geiger
Check out the Scanlan Group's latest publication by Alby Benny about the photochemical macrocyclisation of thiolactone peptides via acyl thiol-ene. 💡💡💡 doi.org/10.1039/D4CC02…
Today we are publishing evidence from our Institutes to show the impact of changes to the UK immigration system on cancer research. We call on the new UK Government to reduce costs and review the system so it works for research - to meet their ambitions for health and growth.
Such a pleasure to be one of the poster winners! Lovely conference, it was great to meet so many new people and hear about exciting research in Chemical Biology 🥰
End to a great conference in Galway with the Poster winners, congratulations! Congratulations and thanks to Eddie Myers, Marina Rubin’s, and Eddie’s research group for all their efforts @irishchemistry @uniofgalway
From this week's covers: Sidechain- and backbone-modified lasso peptides were produced via a chemoenzymatic approach, offering a promising framework for designing peptide-based drugs. @UZH_Chemistry @NinaHartrampf Learn more ➡️ go.acs.org/a2g
Excited to share our latest paper in @J_A_C_S! Our collaboration with the Honjo group lays the foundation for developing small-molecule activators of antitumor immunity, offering potential in combination with PD-1 cancer therapy. pubs.acs.org/doi/10.1021/ja…
Our chemoenzymatic synthesis of the lasso peptide Microcin J25 is out now in @J_A_C_S! We used flow-SPPS to synthesize several sidechain- and backbone-modified precursor peptides and demonstrated their in vitro transformation. pubs.acs.org/doi/10.1021/ja… @UZH_Chemistry @Hartrampf_Lab
A postdoc position is open to join our group @ChemistryatYork working on organic electrolytes together with @NIMS_PR - apply by 15 May at jobs.york.ac.uk/vacancy/pdra-i…
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