@blueprint_eu Profile picture

Blueprint

@blueprint_eu

BLUEPRINT - a BLUEPRINT of Haematopoietic Epigenomes - is a large-scale FP7 research project receiving close to 30 million euro funding from the EU.

Joined October 2013
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Blueprint Reposted

@blueprint_eu the gift that keeps on giving after more than ten years from its inception

Do genetic risk variants for psychiatric disorders implicate immune cells? 🌟Yes!🌟"Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells" out now in @NatureComms nature.com/articles/s4146…



Blueprint Reposted

New #compubio @ImdeaAlimenta work in collaboration with Anke K Bergmann (MHH) @blueprint_eu An epigenomic description of T-LGL pediatric leukemia identifiying BCL11B as a potential biomarker @BioMedCentral Leaded by Patricia Johansson & @teresa__laguna …lepigeneticsjournal.biomedcentral.com/articles/10.11…


Great to see that @blueprint_eu teams are still publishing about data generated within this Eu project. Congrats @nicolesoranzo @BiolaMJavierre and others

Do genetic risk variants for psychiatric disorders implicate immune cells? 🌟Yes!🌟"Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells" out now in @NatureComms nature.com/articles/s4146…



Blueprint Reposted

We adapted the excellent @blueprint_eu policies created by @PaulFlicek and others into a "Policy for processing data access requests". Following some changes by the @UHN_Research Genomics Data Access Committee, we deposited the final policy on @ZENODO_ORG doi.org/10.5281/zenodo…


Interesting paper on communicating epigenetics to the public.

Do genetic risk variants for psychiatric disorders implicate immune cells? 🌟Yes!🌟"Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells" out now in @NatureComms nature.com/articles/s4146…



Blueprint Reposted

Another contribution to science by the evergreen @blueprint_eu dataset. Great work @BrancoLab

Impressive talk by Ozgen Deniz (@BrancoLab) studying oncogenic cis-regulatory activity of HERV LTRs in AML using epigenomics profiling and editing! nature.com/articles/s4146… #cshlTE20



Blueprint Reposted

Interested to learn more? Find the full 10-year strategy to implement cell-based #interceptivemedicine in #Europe in the #LifeTimeSRA ➡️bit.ly/3m0ONP6

LifeTimeIni's tweet image. Interested to learn more? Find the full 10-year strategy to implement cell-based #interceptivemedicine in #Europe in the #LifeTimeSRA
➡️<a style="text-decoration: none;" rel="nofollow" target="_blank" href="https://t.co/nLSqztQW1C">bit.ly/3m0ONP6</a>

Blueprint Reposted

A9. 4/(b) Controlled-access data (through @EGAarchive or dbGaP) with a data access policy that maximizes access to the data for responsible researchers. The @blueprint_eu project's guidelines is a good example. #ASHGtalksData blueprint-epigenome.eu/index.cfm?p=B5…


Blueprint Reposted

Great collaboration with @guilbourque and colleagues using @blueprint_eu data

1/3 New finding! Up to 5% of chip-seq peaks change if we use a personalized or graph genome. See below for a figure showing a peak found only using a graph genome. genomebiology.biomedcentral.com/articles/10.11…

guilbourque's tweet image. 1/3 New finding! Up to 5% of chip-seq peaks change if we use a personalized or graph genome. See below for a figure showing a peak found only using a graph genome.

<a style="text-decoration: none;" rel="nofollow" target="_blank" href="https://t.co/NpMTdvhfJX">genomebiology.biomedcentral.com/articles/10.11…</a>


Blueprint Reposted

#Ensembl100 💯 brings a new interface for configuration of multidimensional trackhubs, such as @blueprint_eu! Here’s how to use it: buff.ly/2Yjbc0v #trackhub #opendata

ensembl's tweet image. #Ensembl100 💯 brings a new interface for configuration of multidimensional trackhubs, such as @blueprint_eu!
Here’s how to use it:
<a style="text-decoration: none;" rel="nofollow" target="_blank" href="https://t.co/GJOuJ4x6UC">buff.ly/2Yjbc0v</a>
#trackhub #opendata

Good to see the long lasting collaborations of @nicolesoranzo and @GuigoLab resulting from @blueprint_eu Also a nice reminder of first annual meeting we had @CRGenomica

Always a pleasure to visit beautiful @CRGenomica and to see friends. Thank you @GuigoLab for fabulous hospitality @blueprint_eu @anavinuela @arnsbr

nicolesoranzo's tweet image. Always a pleasure to visit beautiful @CRGenomica and to see friends. Thank you @GuigoLab for fabulous hospitality @blueprint_eu @anavinuela @arnsbr


Great to see that the @blueprint_eu data continue to being used. Thank you @kousikbioinfo and @Soranzoteam !

Here we extend the evaluation of regulatory QTLs generated as part of the @blueprint_eu project (Chen et al., Cell, 2016) to systematically map molecular mechanisms and causal variants at 12 different immune-mediated diseases with publicly-available summary statistics. 3/15

kousikbioinfo's tweet image. Here we extend the evaluation of regulatory QTLs generated as part of the @blueprint_eu project (Chen et al., Cell, 2016) to systematically map molecular mechanisms and causal variants at 12 different immune-mediated diseases with publicly-available summary statistics. 3/15


Great job of all people involved @Kate_Sci, @luigra1, @Ciavenasc, @laurastephen, @PaulFlicek, @henkstun and many other members from @blueprint_eu

Here we extend the evaluation of regulatory QTLs generated as part of the @blueprint_eu project (Chen et al., Cell, 2016) to systematically map molecular mechanisms and causal variants at 12 different immune-mediated diseases with publicly-available summary statistics. 3/15

kousikbioinfo's tweet image. Here we extend the evaluation of regulatory QTLs generated as part of the @blueprint_eu project (Chen et al., Cell, 2016) to systematically map molecular mechanisms and causal variants at 12 different immune-mediated diseases with publicly-available summary statistics. 3/15


Great to see this publication in @NatureComms from former @blueprint_eu members @idibaps

A new paper together with our collaborators at @idibaps @hospitalclinic, integrating #CLL #Genetics and #epigenetic information, is now out in @NatureComms Funding @blueprint_eu @bloodwise_uk @CRUKresearch nature.com/articles/s4146…



Congratulations to @nicolesoranzo, partner of @blueprint_eu for being elected new member of @EMBO!

(eg @blueprint_eu), #European postdocs and students (eg @LoryBomb @d__vuckovic @lisalyliton @kmw1000 @manueltard), #European visiting students (eg @macsx82), and the #European scientific community at large. I hope that the UK community can find a way to continue



Blueprint Reposted

I will talk about the blueprint data analysis portal to exploit @blueprint_eu data by non bioinformaticians blueprint-data.bsc.es/release_2016-0…


Blueprint Reposted

And this afternoon talking about the huge work done by @blueprint_eu colleagues and the potential of data reuse. With focus in our work @Alfons_Valencia @danielrico_bio @VeraPancaldi @david_de_juan @JMFernand3z @SimoneEcker @vdelatorrelabs Felipe Were

esantapau's tweet image. And this afternoon talking about the huge work done by @blueprint_eu colleagues and the potential of data reuse. With focus in our work @Alfons_Valencia @danielrico_bio @VeraPancaldi @david_de_juan @JMFernand3z @SimoneEcker @vdelatorrelabs Felipe Were

Blueprint Reposted

And onThursday talking about the @blueprint_eu project and our work on it invited by @navarrabiomed and @ONCONET_SUDOE onconetmbcb.eu


Blueprint Reposted

New software package from some of our IHEC and @blueprint_eu PIs: "RnBeads 2.0: comprehensive analysis of DNA methylation data" - Fabian Müller et al @GenomeBiology genomebiology.biomedcentral.com/articles/10.11…


Blueprint Reposted

More on neutrophil genetics from us at @SoranzoT + collaborators @mikhailspivakov amongst others. A profile of haematopoietic TF, PU.1 in primary neuts from ~100 individuals from the @blueprint_eu variation panel, combined with promoter capture HiC biorxiv.org/content/10.110…


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