Juewen Liu
@bionalooProfessor of Chemistry at UWaterloo working on #Aptamers #DNAzymes and #Biosensors. Editor of Biosensors & Bioelectronics, TrAC, CCL, and FACETS.
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we isolated a 10 nM Kd aptamer for quinine, with no binding to cocaine. Now, finally, both quinine and cocaine have their own aptamers. Another good collaboration with @philip_johnson8, an expert on this topic. Open access, free to read💥 …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ch…
Gave three talks in Taiwan, National Taiwan University, National Tsing Hua University, and Chang Gung University. Had a great time meeting with old and new friends and collaborators. Last in Taiwan was 7.5 years ago. Seems lost a few pounds.
Excited to see this paper marked as a Very Important Paper (VIP). We put some thought into the lowest target concentration during aptamer selections. Check it out, open access 💥
#ChemBioChem Exploring the Lower Limit of Target Concentration in Capture-SELEX Using Guanine as a Model Target (Juewen Liu and co-workers) @bionaloo onlinelibrary.wiley.com/doi/10.1002/cb…
Just gave a talk in the Chemistry Department at the University of Central Florida. Good discussion, nice weather and beautiful campus
Be sure to read research from @bionaloo & co @UWaterloo on the possibility of obtaining buffer binding aptamers in failed SELEX Find their full report on our website👇 pubs.rsc.org/en/content/art…
I think this is a good method to make Spherical Nucleic Acids. We are using it in the lab now, and some experiments that we did not want to do because of the cost of thiolated DNA can now be done. Try it out 👍
Rapid Thermal Drying Synthesis of Nonthiolated Spherical Nucleic Acids with Stability Rivaling Thiolated DNA (Juewen Liu and co-workers) @bionaloo @WaterlooChem #OpenAccess onlinelibrary.wiley.com/doi/10.1002/an…
Proudly completed reviewing 1000 manuscripts for ACS publications in 16 years. Mostly for @ACS_Langmuir @an_chem @J_A_C_S @ACS_Sensors @acsnano I have to decline probably 75% of the invitations though. Published 177 ACS papers, a review-to-publication ratio of 5.65👏👏
Just finished my first RNA conference, but it seems the few DNA aptamer guys still phase separated.🤣
Heavy rain this morning but went for a run anyway. Finished my talk at #RNACanadaARN yesterday. Looking forward to day 3 of the conference 👍
We always wondered about the possibility of obtaining buffer binding aptamers for failed SELEX. Now we know it is unlikely, especially when Good's buffers are used. A nice collaboration with @philip_johnson8 pubs.rsc.org/en/content/art…
our new review paper led by an AMTD postdoc in my lab, Dr. Vasily Panferov, summarizing using the optical and catalytic properties of nanomaterials for signaling, just published in Advanced Optical Materials - @AdvOpticalMat onlinelibrary.wiley.com/doi/10.1002/ad…
Our new method for attaching unmodified DNA to gold nanoparticles by heating published in @angew_chem most importantly, cost-effective. We use it in the lab now. Welcome to try! 👏👏 onlinelibrary.wiley.com/doi/10.1002/an…
had an 8 hour layover in San Francisco. Sneaked out of the airport and visited @Atilabio in Silica Valley. Very nice discussion 😃
Very pleased to be invited to give a talk at the nanozyme conference in Wenzhou. Visited a gorgeous waterfall in Mount Yandang with a height of 197 meters 👍👍
Had a great time hiking with my PhD advisor and Yingfu and a few other friends to climb Mount Taishan. Nearly 7000 steps and certainly more than 7000 people!
A great collaboration with my UWaterloo colleagues. This journal has a good impact factor now👏👏
Exploring the catalytic degradation of microplastics: towards protecting water and sediments onlinelibrary.wiley.com/doi/10.1002/EX… @UW_Ecohydrology @bionaloo @GWF_pubs
Just finished my talk in this great DNA nanotechnology conference in Jinan, China. A beautiful city for jogging too.
Great to see this paper published and be part of this project. A good demonstration of our lactate aptamer for electrochemical sensing. Good collaboration with @Mahla_Poudineh and @SoleymaniLab👏👏
Exciting new technology together with @Mahla_Poudineh for monitoring lactate and glucose in vivo using aptamers. Congrats to @ElahehB1992 and Hanjia Zhang. Great collaboration with @bionaloo and @SchertzerLab onlinelibrary.wiley.com/doi/10.1002/ad… @McMasterU @UWaterloo @NSERC_CRSNG
wanted to get an insulin aptamer, ended up with zinc aptamers...🤣
Don't miss "Unexpected enrichment of DNA aptamers for Zn2+ ions from an insulin selection" by Yibo Liu, Xiaoqin Wang and Juewen Liu @bionaloo Read the full communication here 👇 buff.ly/3Rrwns4
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