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@wellingtonhemat
@fabiopss
@mariana_guarana
@lucascantadori
@scheinbp
@isaisabelagap
@GuiperiniMD
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@fernandahemato
@DrRenatoCunha
@Cortopassi_GM
@UjjaniC
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#Myeloma Paper of the Day: Brazilian study of real-life experience of myeloma (MMyBRAve) finds improvement in outcomes (median OS in transplantation-ineligible and eligible patients of 49 & 93 months), but remaining diagnostic and therapeutic gaps: pubmed.ncbi.nlm.nih.gov/39488485/. #mmsm
Salles et al 5 yr results of POLARIX 1L RCT PolaRCHP vs RCHOP in IPI 2-5 DLBCL 5-year PFS estimates 64.2% vs 59.1% HR 0.78; 95% CI: 0.623-0.980 5-year OS 82.2% vs 79.6% not significant #ASH2024 #lymsm
CONGRESS | #IMS2024 | PRESENTATION Abel Costa @anetoc shares findings from a trial of sonrotoclax + dexamethasone in patients with RRMM harboring t(11;14) mutations (N=32). The ORR was 75% among 24 efficacy-evaluable patients, with a ≥ VGPR of 50%. The combination was well…
R/R T-ALL. Therapeutic approach. - How I treat, blood journal 2023. - ESMO guidelines 2024. - ELNetwork guidelines 2024. - NCCN guidelines 2024. What is the best scheme before the alloSCT (antiCD38, Bortezomib, VEN…) ?
Great presentation by Suzanne Lentzsch on Linvoeltamab on RRMM - ORR 71% ,CRS 46%, and a high PFS (70%) at 12mos - need to see if this holds up - ? Best in class or selection bias- too early to tell
Next generation CAR with novel binding domain! Deep and durable response in high risk patients! Look forward to getting this to our patients! @MCWCancerCenter @EHA_Hematology #eha2024
Guideline paradigms in EMD @JHillengass at #IMWG2024. @Myeloma_Society #mmsm
Check out our poster at #EHA2024 with safety and efficacy data from the Ph 1/2 study with Golcadomide +/- Ritux for R/R FL @GuiperiniMD
Results GHSG HD21 BrECADD v eBEACOPP in 1L cHL #ASCO24: - 1500 pts, med age 31, Stage IIB 17%, rest adv stage - PFS superior in BrE arm: 4 yr 94% vs 91% (!!!) - less tox & neuropathy with BrE - 96% gonadal recovery with BrE (73% with escB) New standard of care in cHL? #lymsm
First of the @NEJM #ASCO24 myeloma papers that I will be highlighting. Congrats @dra_v_hungria @mvmateos @thanosdimop et al. nejm.org/doi/full/10.10…
Interested to see EPCORE-CLL1 update: epcoritamab for Richter's transformation, now n=35 - ORR 50%, CR 35% - higher in treatment-naive subgroup - promising signal for a difficult-to-treat disease - combinations likely the way forward here #lymSM #EHA24 library.ehaweb.org/eha/2024/eha20…
Classic Hodgkin Lymphoma in Adolescents and Young Adults: on line and in print @JCO_ASCO Enjoyed working on this with @KaraKellyMD ascopubs.org/doi/full/10.12…
How I manage bone modifying agents (BMAs) in #myeloma to avoid jaw osteonecrosis: #mmsm - Obtain dental eval before starting BMAs - If pending invasive dental procedure, advise holding BMAs 2-3 months before and after - Dental exams every 6 months Ref: mdpi.com/2072-6694/13/1…
Amazing results for older HL! #ASH2023
T-cell lymphoma. Flow Cytometry approach. Key points.
The total mass, number, & distribution of immune cells in the human body | PNAS pnas.org/doi/full/10.10…
"The existence of two acute myeloid leukaemia classification systems...is concerning... and threatens the ability to... deliver appropriate... management strategies" NEW Viewpoint—Standardising acute myeloid leukaemia classification systems #leusm thelancet.com/journals/lanha…
#Glofitamab approved in Europe for r/r DLBCL. The CD20×CD3 bispecifics are the most potent single drugs so far tested in this indication, I hope they will be made available #lymsm globenewswire.com/news-release/2…
A collection of clincally important insights in myeloma and MGUS. #MedTwitter 1/ Serum protein electrophoresis may underestimate the true size of the M protein when the level is too high. The gel saturates. So go by the quantitative IgG/IgA level to get a better estimate of M…
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Who to follow
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Wellington Fernandes
@wellingtonhemat -
Fabio Pires
@fabiopss -
Mariana Guarana
@mariana_guarana -
Lucas Cantadori
@lucascantadori -
Phillip Scheinberg
@scheinbp -
Isabela
@isaisabelagap -
Guilherme Perini, MD
@GuiperiniMD -
Eduardo F O Ribeiro
@EduardoFlavioO1 -
Fernanda Santos
@fernandahemato -
Renato Cunha, M.D.-Ph.D.
@DrRenatoCunha -
Gabriel Cortopassi
@Cortopassi_GM -
Chaitra Ujjani, MD
@UjjaniC -
The Fellow On Call
@TheFellowOnCall
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