Andy D Lee
@andy_d_leeCofounder @vincerebio bridging AI and Biology. On a mission to conquer age related decline.
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If you want this shift, @theA4LI is leading the charge for policy change and reallocation of $ toward longer, healthier lives.
We focus almost all of our care around diseases. The US has a disease-care system. We do pretty much the same thing with our research dollars. The majority of the NIH budget supports disease-related research. We need a science of healing. What keeps people well and thriving?
Anyone remember the 90's game Burn Cycle? Heartbreaker from I Hate Models is triggering flashbacks. open.spotify.com/track/0Y3SRdVn…
Awesome new initiative led by Vincere SAB member Dr Dario Alessi at @dundeeuni to translate LRRK2 insights into new therapies for Parkinson's disease.
Excited to try this! p.s. Flashback to 2022 when we used NetworkX to develop cell-type specific networks to identify new drivers of mitochondrial disruption in Parkinson's disease: pmc.ncbi.nlm.nih.gov/articles/PMC93…
📣 Just announced: NetworkX accelerated by NVIDIA cuGraph is generally available, bringing speed and scale to the most popular #Python graph analytics library. 👀 Experience up to 500x speedups on large graph workloads in NetworkX with zero code changes. Tech blog ➡️…
Ever wanted to share a VC pitch experience - or get insights from others who have been down that road before? Check out pitchdeckprefs.com
Spring and I have been talking for years about the potential for "Free-range science" and the Agouti caught my eye in Vitalia as a great model to observe - very cool to see that others are diving in and publishing characterization!
🚨Fun Rodent alert ‼️ I’m excited to share a review of what is becoming one of my passion projects since around 2019, that blossom at @PennSAS . The future of Natural Neuroscience with the Agouti! Published today in Ethology. Sooo, What is an Agouti? 🧵 onlinelibrary.wiley.com/doi/10.1111/et…
Longevity Global Boston is hosting a bites and drinks event on reversing your brain aging October 30th in conjunction with @agingbiomarkers conference. RSVP: lu.ma/nfc9c9j7
At #StatSummit Anne Carpenter shared images showing that mitochondria distribute through the cell differently in bipolar patients compared to controls - in skin cells, highlighting the way mechanisms are not limited to the cells you might think of as linked to a disease.
Europe – we need your help. Please sign this petition to create a pan-european legal entity and promote it as much as you can: eu-inc.org We got RIGHT NOW a once in a generation chance to improve Europe for startups. 🔥 We got 6 weeks until the new comission sets…
Short report: The state of the mitochondria portion of the aging biotech field: 50 companies! $1.4+B raised 700+ people 150+ clinical trials many MoAs/targets: mitophagy, transplant, fission, NAD+, UrolithinA, CD38, PINK1, PPARδ, DRP1, USP30, Complex 1, OMA1, & more Read on:
This is indescribably important. The E&C committee doc was a starting-point, but will do more harm than good without changes like this. PLEASE sign and advocate to others - especially gerontology luminaries and anyone with decision-making influence. Massive kudos to A4LI!
Thank you to those we have shared and sign your support for our proposal for a new National Institute for Longevity and Aging Research (NILAR). We've reached 300 signatures so far! The U.S. faces a demographic shift with an increasing proportion of individuals aged 65 and older,…
You beat me to it! See here for all the Dublin 2024 talks: youtube.com/@longevitysumm…
How rejuvenating mitochondria can stop Parkinson's and Aging - @andy_d_lee at the #LongevitySummitDublin with @aubreydegrey and LEV Foundation youtu.be/6G5rE7sVlaw
How rejuvenating mitochondria can stop Parkinson's and Aging - @andy_d_lee at the #LongevitySummitDublin with @aubreydegrey and LEV Foundation youtu.be/6G5rE7sVlaw
I’d really like to see the FDA move to a 2 stage approval decoupling safety and efficacy. If safe anyone can buy (with appropriate labeling for who “safe” was tested with and how) Effective requires placebo controlled trial meeting endpoint. Both -> approved for prescription.
Experienced athletes learn to schedule more easy days than hard, but no matter how good you get, the days spent flirting with max will always suck. You just crave the pain and the gains on the other side.
Proud scholar step down from your summit fall in love and become a fool! Become humble like dust walk with everyone good and bad, young and old so one day you may become a king. — Rumi
This was key to forming @VincereBio - human data can stack the deck for successful human drugs. I’ll go a step further and say genetics + multi-omics put you even closer to the goal.
Many of you might be aware of the commonly quoted success rate of ~10% in drug development. One of the efficient ways to rise this number is to add human genetics insights into the pipeline, as illustrated in the below plot from a 'Views and News' article I contributed to…
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Who to follow
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Vincere Bio
@VincereBio -
Alan Tomusiak
@alantomusiak -
Sebastian A. Brunemeier 🏴 🌎 💊 🧬
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Mark Hamalainen
@MarkHamalainen -
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@amos_schorr -
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Carol
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