Ahmed Bedair
@ahmedoncConsultant Clinical Oncologist
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Special thanks for our colleagues from Clattebridge Cancer Centre and the Christie @CobbenDavid @Abutalebmk who made a special appearance in the Autumn Scientific meeting of Northern Ireland Society of Oncology. @CCCNHS
NISO educational meeting in the NWCC. ESMO updates, frailty, SABR and protons
Northern Ireland Society of Oncology (NISO) Autumn scientific meeting. A wonderful afternoon with colleagues from all over Northern Ireland. Lovely updates with a bit of humour. #NWCC #NISO #NICC #westernHSCTrust
Osimertinib use associated with nutritional deficiencies ❗️Significant deficiencies of Vit B, Vit D, Iron, Vit B12 ❓May reflect GI side effects of drug 🤔 Should screen for these during Osimertinib treatment: quick and cheap to do #ASCO24 #LCSM
TRANSMET: CT+liver transplant vs CT alone in pts with unresectable CRC liver mets - 94 pts - 5-year OS in ITT: 57% in CT+LT vs 13% in CT arm (HR 0.37,p=0.0003) - 74% of transplanted pts had recurrences in one or more organs. - anybody else feeling like🤯🤯🤯🤯? #ASCO24
Day 1 #ASCO24 Highlights: 1. #CROWN: Lorlatinib in ALK mNSCLC 2. #PALOMA3: SC #Amivantamab in EGFR mNSCLS 3. #MARIPOSA: Ami in EGFR mNSCLC 4. #GlobalOncCoP @inas_md 5. #SocialMedia: Leveraging this @fumikochino @lungoncdoc #OncTwitter #MedEd #MedTwitter @ASCO #lcsm 1/6
📢🚨#ASCO24 plenary @DavidRSpigel - pivotal ADRIATIC ph III trial; adjuvant durvalumab arm after chemoradiotherapy (cCRT) ± PCI in small cell #lungcancer; ⬆️ OS (HR 0.73), median OS 55.9 vs 33.4 for placebo. Grade 3/4 AEs in 24.3% vs 24.2%. 💥Practice changing!!! #radonc #lcsm
The new standard of care is consolidation immunotherapy for limited stage small cell lung cancer & the first systemic therapy advance for limited small cell in ~50yrs. Allied to Laura we had fun on the @ASCO non-metastatic NSCLC/SCLC/meso track committee this year! #lcsm #ASCO24
Impressive increase in PFS with consolidation osimertinib after CRT for pts w unresectable stage III lung cancer. Crossover on progression 82% higher than in most other studies. OS far from mature. Will be adopted as a new standard where it is available I believe. #lcsm #ASCO24
Consensus guidelines on the diagnosis and management of RT pneumonitis ▶️ Delphi consensus ▶️Practical guide to assess risk in individual patients ▶️unmet need-> clarify the relationship between RT-drug-induced pneumonitis + optimal management strategies sciencedirect.com/science/articl…
Here are the slides from the ORATOR2 trial. Key takeaways (short 🧵) - RT meets primary endpoint compared to historical control - OS and PFS significantly better in RT arm.
First prospective data of SBRT for early stage NSCLC in pts with interstitial lung disease 👉 risk of treatment-related mortality 7.7% 👉 median OS 25mo 👍 prespecified acceptability thresholds for toxicity & efficacy met 👏 @drdavidpalma and colleagues jamanetwork.com/journals/jamao…
What an outstanding achievement for our physics department. They are truly the heart and soul of NWCC radiotherapy services. Well done 👏👏👏 @WesternHSCTrust @UKAS
RT Physics delighted to maintain accreditation to BS 70000:2017 MPACE. 1 of only 2 UK RTP depts to hold this. Couldn’t have achieved without the collaboration of our wider RT colleagues. 🎊@WesternHSCTrust @UKAS #RTPhysics #MPACE
🌟 Summary - Lung 🫁 & Solid tumors 👤 📍 ADCs 📍 BsAbs 📍 I-Os 📍 Cancer Vaccines 📍 Oncolytic Viruses 📍 CAR-T cells 📍 TILs 🔈 References are numerous. 1/22
I wonder if same-day adaptive radiotherapy using CBCT without prior CT simulation is going to be the standard workflow for palliative treatment in the near future
New article (Vol. 192) Evaluating AI-generated CBCT-based synthetic CT images for target delineation in palliative treatments of pelvic bone metastasis at conventional C-arm linacs Nienke Hoffmans-Holtzer et al. doi.org/10.1016/j.rado… thegreenjournal.com/article/S0167-…
It’s World Cancer Day and with the NI Government back our priority must be the implementation of the 10 year cancer strategy➡️ health-ni.gov.uk/publications/c… #WorldCancerDay @WesternHSCTrust @HSC_NI @niassembly
Can you believe it’s been 730 days since Northern Ireland had a functioning government? In this time, people with cancer have sadly become the collateral damage of the Assembly’s collapse. Latest figures show only 34% of people with cancer in Northern Ireland started their…
Good luck Hoda @HedySAty
📢🌟 Excited to be the ONLY trainee candidate for the RCR Clinical Oncology Specialty Training Board! Keen to hear your training challenges. Committed to mentorship and educational innovation.Let’s shape a dynamic future for our workforce! Vote now open!🗳️ #ClinicalOncology
Give a shout out to the amazing achievement of NWCC radiotherapy team 🎉🎉🎉 #NWCC #NWCC_LegenDerry @RTTQA_UK @radiotherapy_uk
Our Radiotherapy Team, North West Cancer Centre have successfully completed a full inspection from CHKS. CHKS surveyors assessed the team against 513 criterion and found the NWCC Radiotherapy service to be 99.6% compliant, with only 2 partial compliances and 0 non-compliances
Great series of live webinars addressing a hot topic. Thank you @ESTRO_RT for making it available free.
📆 Save the Date: The next webinar of our #Reirradiation Series is set for Monday 4 December 3-4 pm CET. Join us as we delve into the theme of "Practical #Radiobiology for Clinical Reirradiation Challenges." ✅ To secure your spot, register here : bit.ly/3N59l87 #radonc
ctDNA+/-radiologic tumor volume is prognostic in early stage NSCLC: - 85pts+32pt validation cohort, analysed by tumor agnostic assay - pre-Tx ctDNA assoc w ⬇️RFS/OS - pts w ctDNA clearance=similar RFS/OS as pts w undetectable ctDNA #LCSM @Annals_Oncology annalsofoncology.org/article/S0923-…
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Who to follow
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NI Cancer Trials
@nicancertrials -
Angela McKeever
@angelamckeeever -
Karen Bradley
@karenebradley -
Shahreen Ahmad
@Shahreena17 -
Ciara Lyons
@ciaralyons -
Mary Costelloe
@MaryCostelloe10 -
Cara Anderson
@CaraAnd16564794 -
Aisling Haughey
@aisling_789 -
David Cobben
@CobbenDavid -
Lois Mulholland
@lemulholland -
Hossam Abdulkhalek MD MSc CPHQ FRCP
@HossamRAOnco
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