Anna Cieślak
@aa_cieslakMolecular Pharmacologist | Drug Discovery | Stem Cell Expert | Data Analyst | Former President of CU Postdoc Society
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4 papers @Nature today on extrachromosomal (ec)DNA and cancer —Present in 17% of cancers —Suppresses the immune response —Prognostic significance (figure) nature.com/articles/s4158… @CharlesSwanton and colleagues
Hot off the press. Excited to share work done by stellar @UroOnc fellow @AmandaMyersMD mentored by @UroDocAsh Further advancing knowledge on aggressive #bladdercancer subtypes. T1 nonmuscle invasive small cell neuroendocrine carcinoma 🔗 sciencedirect.com/science/articl…
Blog post on using AI in academia with @DrAnneCarpenter and the great folks at @Mid_Career_PI! arjun-raj-lab.gitbook.io/arjun-rajs-too…
Almost everyone in microscopy (especially LSFM) talks about data deluge, but the tools haven't kept apace with the problems. Check out PetaKit5D for processing and analyzing your huge datasets!
Out today from Ruan, Betzig, Upadhyayula and colleagues! PetaKit5D offers versatile processing workflows for petabyte-scale light sheet microscopy data. nature.com/articles/s4159…
Brilliant hard work to create a benchmarking framework to show convincingly that the whole field of gene expression forecasting (perturbation predictions) has deep problems (as shown by several other recent benchmarks), especially the fancy single cell foundation models. 1/
Today, I'm excited to present the second big chunk of my Ph.D. work. We are building a thorough assessment of the burgeoning field of gene expression forecasting. Something is deeply wrong.🧵 - Preprint: biorxiv.org/content/10.110… - Code: github.com/ekernf01/pertu…
I highly recommend joining Marcin's team. I know him personally, and he is an incredibly knowledgeable and open-minded scientist. Feel free to reach out to him with any questions.
Our team in Orléans (France) is looking for a new postdoc, to work closely with a research associate, Ibtissam Talhaoui, on a project focused on potential SUMO E3 ligases targeting the nucleosome. The details here: emploi.cnrs.fr/Offres/CDD/UPR…
There is still time to register for this FREE VIRTUAL SYMPOSIUM on Spatial Biology organized by myself and my colleagues at @naturemethods @naturegenet @NatureBiotech and @nature! Check out the amazing line up!
Please join us for our free Technology Live Virtual Symposium on Spatial Biology this October 29th! natureconferences.streamgo.live/spatial-biolog… Speakers include Rong Fan, Andrea Radtke, Long Cai, Sarah Teichmann and many more!
Highly recommended
Postdoc positions available! Carpenter-Singh lab Broad Institute of Harvard and MIT Cambridge MA USA $70,000 (more with years of experience post-PhD) flexible start date See next post for project details... Pls RT! More here/apply: docs.google.com/document/d/1R5…
Do you know/have/are high-school students interested in #AI for #DataScience? We've developed a 5-session course with @therobohub for 5 Saturdays from Oct 19-Nov 16, covering (1) data science, (2) predictive modeling, (3) AI agents, (4) data scraping, and (5) the integration of…
Great mechanistic paper from an amazing group, highlighting a critically important cell type they discovered - but Truth has to be said - beyond that first wave - post COVID persistent fibrosis is extremely rare.
How Covid can lead to extensive lung fibrosis (scarring): the role of alveolar macrophages @NatImmunol @Misharin_lab @Sander_Lab nature.com/articles/s4159… nature.com/articles/s4159…
I still think this is a great idea, to look for drugs that mimic whatever is going on with centenarians and those who age well! Maybe the time is more ripe now, anyone know databases of protective/healthy/anti-aging alleles?
Anyone know a database of protective/beneficial alleles? I want to identify small molecule mimics for each, using Cell Painting/profiling.
I just updated my free, online e-book 📘, "Applied Geostatistics in Python: A Hands-on Guide with GeostatsPy!" The formatting is cleaner 🧹, and I’ve added more detailed descriptions 📝. I promised it would be a living document—and it’s alive! 🌱 Check it out here:…
Achieving optical transparency in live animals with absorbing molecules | Science science.org/doi/10.1126/sc…
Oh, hey! My talk video is online if you'd like a tutorial on AI in preclinical drug discovery: "Phenomics in Drug Discovery: Microscopy and Machine Learning" from the 2024 Machine Learning for Drug Discovery Summer School hosted by Mila/@valence_ai youtube.com/watch?v=mc3vVx…
Cell biologists! This is a fantastic statistics primer custom made for you. Very practical, must-read! From Pollard lab five years ago: molbiolcell.org/doi/10.1091/mb…
Popov lab is hiring! Join our fast-paced, multidisciplinary biomedical research team to study the role of mitochondria-derived DAMPs (and beyond) in liver cirrhosis and its sequelae. Recent PhDs and experienced postdocs apply here bilh.wd1.myworkdayjobs.com/External/job/B… @BIDMC_GI
The Bioimage Analysis Postdoc Training Program has been hugely satisfying - teaching useful skills to biologists. Largely run by Beth, we have described the program in a new preprint!
Fresh out on biorxiv - me getting to brag about the stupendous, brilliant, AMAZING folks who have been kind enough to come hang out with us at the @broadinstitute to do our Postdoctoral Training Program in #BioimageAnalysis . Into the 🧵for story! (1/7) biorxiv.org/content/10.110…
wwLearning the language of proteins and predicting the impact of mutations biorxiv.org/content/10.110…
The choice of whether to use Seurat or Scanpy for single-cell RNA-seq analysis typically comes down to a preference of R vs. Python. But do they produce the same results? In biorxiv.org/content/10.110… w/ @Josephmrich et al. we take a close look. The results are 👀 1/🧵
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Who to follow
-
CU Postdoc Society
@CUPostdocs -
Bianca Jones Marlin, PhD
@bjmarlin -
This Podcast Will Kill You
@tpwky -
Libby Jackson
@LibbyJackson__ -
Rafael Carazo Salas
@RafaCarazoSalas -
Evelien Adriaenssens (she/her)
@EvelienAdri -
dormant
@soozaphone -
Naveed Tavakol, PhD
@naveedtavakol -
Ankur Sharma
@asharmaiisc -
UCDavis_Gene_Therapy
@UCDavisGT -
Dr. Caroline Bartman
@Caroline_Bartma -
RareCyte, Inc.
@RareCyte -
Susana C. Gonçalves, PhD 🍄👩🏻🔬 💪💬
@cfe_mycolab -
Dr. Holly Hunsberger
@HunsbergerLab -
Marie Labouesse
@LabouesseMarie
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