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BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
KR is widely used in academic & pharmaceutical industry. One could use L-protease to separate peptide epimers, instead of mirror-image L-protease, work from @lab_mueller showed D-protease is a powerful tool to separate protein epimers enabling stereoselective protein modification
Kinetic Resolution of Epimeric Proteins Enables Stereoselective Chemical Mutagenesis | Journal of the American Chemical Society @kclchemistry @KingsCollegeLon #Kinetic #Resolution #Epimeric #Proteins #Stereoselective #Chemical #Mutagenesis pubs.acs.org/doi/10.1021/ja…
A recap of 53-day Chang’e-6 lunar mission. Launch, lunar landing, sampling, ascending, and returning back to earth! Full HD: m.youtube.com/watch?v=hHN6KP… #ChangE6 #News #LunarMissions @JeanFranoispel7 @physorg_com @wulei2020 @SPACEdotcom @NASA @esa
Geological context of Chang'E-6 landing area and implications for sample analysis More details doi.org/10.1016/j.xinn… #ChangE6 #News #LunarMissions @JeanFranoispel7 @physorg_com @wulei2020 @SPACEdotcom @NASA @esa @SpaceX @GeorgesSalo @isro @ChinaInSpace @SpaceNews_Inc
Chemo-ribosomal synthesis of atropisomeric and macrocyclic peptides with embedded quinolines: chemrxiv.org/engage/chemrxi… Congrats to Isaac Knudson, Taylor Dover, Diondra Dilworth, Cameron Paloutzian, and Hannah Cho, @MillerGroupYale @schepartzlab and @cgem_cci
Happy to share one of my PhD works from Barry lab and @lab_mueller @kclchemistry Now published @J_A_C_S A must read for peptide community, NRPS fan. Big thank to my collaborater @EdwardLambden and all for helping get it out. pubs.acs.org/doi/10.1021/ja…
SAVE THE DATE: PUG Asia-Pacific Online Symposium 12th July 2024 PUG takes on Oceania for our Winter Symposium. Plenary speaker @LiXuechen_HKU Talks available for Melbourne-based PhD students: bit.ly/44mbK5M. Stay tuned for more details! @RACInational @RACI_VIC
Our preprint on “Merging Flow Synthesis and Enzymatic Maturation to Expand the Chemical Space of Lasso Peptides” is now available from @ChemRxiv 🧪🧫. Congratulations to first author Kevin Schiefelbein and everyone else involved 🥳 chemrxiv.org/engage/chemrxi… @Hartrampf_Lab
Thrilled to share that our recent ClusterCAD 2.0 paper from the @Keasling_Lab was featured in a @doescience research highlight! energy.gov/science/ber/ar…
Yay, our latest paper was published last week. The first from my PhD student Sarah Messenger. A bonus as it was published on the day of her PhD defense😁 doi.org/10.1038/s41589…
Congrats Dr. Stephanie "Billie" Heard @zestylollipop on your recent publication characterizing a fungal NRPS gene cluster! Excited to have collaborated with the @therealdiehllab on this project! pubs.rsc.org/en/content/art…
Great talk by Sarah Barry @KingsCollegeLon at #ESBOC56 @ESBOC_Gregynog She talked about the power of natural products to address the challenge of antibiotic resistance. Great insights into biosynthesis that allow bio-inspired (semi-)synthesis of analogs. doi.org/10.1039/D1CC04…
We developed a very cool AI algorithm named CLEAN for predicting enzyme function from amino acid sequence, which was just published in Science today. Congrats to Tianhao, Ocean, Canal, Yunan, and Guangde! news.illinois.edu/view/6367/2166…
Excited to see our work gets published in Angew Chem Int Ed. We enzymatically modify cyclic peptides to allow fluorescent labeling using click chemistry. Have fun reading! Thanks to my wonderful team for their hard work. onlinelibrary.wiley.com/doi/abs/10.100…
Christopher Walsh: 1944-2023 A giant indeed: the impact of his work is staggering. But Chris was even more impressive as a mentor. He was immeasurably devoted to, & loved by, his trainees. Nothing made him happier than doling out his wisdom. Superhuman & human at the same time.
Great presenting my poster at #ISCB2022 in Geneva. Now heading home with ideas and chocolate. I'm grateful for fantastic @RSC_CBBG for my travel grant that allow me to be here @CampusBiotech to present my work @kclchemistry Thanks @NCCR_ChemBio for holding this amazing event.
Very excited to announce our latest paper, 'A Designed Photoenzyme for Enantioselective [2+2]-Cycloadditions', is out now in Nature as an AAP! Congratulations Jonathan, Rebecca and everyone else involved 🎉🎉🎉 nature.com/articles/s4158…
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