Thibault G Sana, PhD @ThibGSana.bsky.social
@ThibGSanaWorking on microalgae at NeoEarth *Born at 348ppm* 🇧🇪➡️🇫🇷➡️🇺🇸➡️🇨🇭➡️🇫🇷
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We recently published a paper @CurrentBiology on a novel and conserved Proteobacterial scaffold observed by #CryoEM formed by BcsD and a Proline-rich partner, bound to cellulose synthase, and involved in biofilm structuration and strength 🦠🔬 cell.com/current-biolog…
After 15 years of academic research, I'm thrilled to announce that I will now join the start-up NeoEarth as Lead Project Engineer, and will help to uncover the biotechnological potential of #microalgae! 🦠🔬 More here: neoearth.fr
Petya @krastevalab, thanks a bunch for welcoming me in your lab, for your constant support, and for making me uncover the world of bacterial cellulose, structural biology and CryoEM 🙏 That was such an exciting time with lots of discoveries, challenges, and wonderful colleagues🥰
It's always bittersweet when one of the fledglings is ready to leave the nest to further their career😌. Thank you @ThibGSana for your humanity, kindness, science and patience with my impatient zeal! All the best in your start-up endeavour and I hope we'll collaborate again soon!
Happy to see this👶out: we crack how E. coli & proteobacteria assemble cellulose secretion systems to recruit proxies for polymer decoration and nM c-di-GMP sensing to diversify a boring synthase with low c-di-GMP affinity and 1 sugar-1 linkage mechanism! nature.com/articles/s4146…
And the work presented is online today 😊🥳 Link: nature.com/articles/s4146…
Superb talk by Itxaso Anso from @krastevalab on the structural characterization of the type II cellulose secretion system. #SecretionDays
Mind-blowing study from Julia Vorholt's lab. They initiated bacterial endosymbiosis in a fungus and followed the system as it became more stable, closer to 'symbiosis'. nature.com/articles/s4158…
Look what I found under the microscope!! 🥰
"The reviewers scored AI-generated concepts as more exciting than those written by humans, although the AI’s suggestions scored slightly lower on feasibility" 😳🤯
The human and AI-generated ideas were evaluated by reviewers, who were not told who or what had created each idea go.nature.com/3XsjoZg
Two papers in @Nature present a new genome editing technique that enables the insertion, inversion and deletion of long DNA sequences at user-specified genome positions. The approach may provide an easier method of genome editing. go.nature.com/3RGkI8M go.nature.com/3RHBvIs
We would like to thank the reviewers for their helpful suggestions
🦠Pathogenic bacterium Pseudomonas aeruginosa breaches lung defenses by targeting mucus producing goblet cells! Intracellular P. aeruginosa may evade immune system and antibiotic treatment, thereby driving chronic infections @NCCR_AntiResist @IHB_Research doi.org/10.1038/s41564…
Latest completed work from our ERC StG BioMatrix is now online 🤩🤩🤩: mechanisms for c-di-GMP sensing and synthase activation by proxy, pEtN-transferase recruitment and polymer modifications @ERC_Research @univbordeaux_EN @iecb_bordeaux biorxiv.org/content/10.110…
Interested in the dynamic mechanisms of the bacterial envelope? Registration for the 1st edition of the "Journées Sécrétion" in Marseille is open until May 31! forms.gle/wCkFzLE4YnRoVP… Organized by Romé Voulhoux @lcb_officiel @CascalesLab @doan_thierry @LISM_CNRS_AMU
Check out the video made by @TULIP_GS_LabEx students in collaboration with @LRSV_Toulouse They studied AMF-associated bacteria and their impact on phosphorus nutrition for mycorrhized plants. Congrats! youtu.be/eLQE1wN5tsg?si…
Looking for a postdoc excited about the structural biology of bacterial biofilms and cyclic dinucleotide signaling. We are a small but diverse and passionate team, have access to high-end facilities and provide hands-on training in a variety of techniques. Repost & DM 🙏🙏🙏
do bacteria hitchhike on surfactants in the #phyllosphere? We believe they do! Read our open access article Microbial Ecology fresh of the press - spearheaded by @micha_kunzler during his BSc thesis shorturl.at/isJP4 @rschlec
Happy to see this paper online. Fantastic work led by @xiaobo_zhong Thanks to the labs of @ManfredWuhrer, @GillesvanWezel and @BriegelAriane for the fruitful collaboration
CslA and GlxA from Streptomyces lividans form a functional cellulose synthase complex @AppEnvMicro by @xiaobo_zhong et al from @ClaessenLAB with @BriegelAriane @GillesvanWezel journals.asm.org/doi/10.1128/ae…
In memoria of an outstanding microbiologist and friend, Pierre Cornelis - Chevalier - 2024 - Microbial Biotechnology - Wiley Online Library …icro-journals.onlinelibrary.wiley.com/doi/full/10.11…
We are happy to announce that the 10th ASM Conference on Biofilms will be held in Portland, Oregon, from Nov 9-13, 2025. We look forward to gathering the biofilm community for what should be a fantastic meeting. See the ASM website for details. asm.org/Events/ASM-Bio…
Biofilm and brains: As part of an awesome team led by @bgyipp and with @stressynomics Altier lab and @KurraschLab, I am thrilled to share a paper showing that P. aeruginosa #biofilm polysaccharides alter sensory-neuron-mediated sickness in lung infection cell.com/cell/fulltext/…
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