Shubham Kumar
@Shu6hamKPhD candidate, MunroLab @MRC_LMB @Cambridge_Uni | @SBSNISER Alumnus | Looking at Golgis in Fly Neurons. Otherwise, hiking somewhere. Tweets my own.
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Interesting preprint! ER-Golgi transport is transcriptionally regulated by Opi1-Ino2/Ino4 circuit, with YIP3, Sec16, Sar1 activity modulated in lipid stress. ER sensing of lipid metabolism drives PRA family-dependent regulation of COPII vesicle transport biorxiv.org/content/10.110…
For the membrane trafficking crowd, we are thrilled to share our BioID map of RAB GTPases! It was a collective effort from many individuals initiated by Benoît, Raphaëlle, and Dominique and followed up extensively by Véronique! Many thanks to everyone! biorxiv.org/content/10.110…
Could there be an evolutionary benefit to ageing? elifesciences.org/digests/92914/…
Wrapping neurites with small light-controlled polymer patches 😮 nature.com/articles/s4200…
Welcome to the #EDRC2025 account of the 28th European Drosophila Conference which will take place in Alicante from the 25th to the 28th of September 2025! Stay tuned for the upcoming news!
Much of the success of breakthroughs, such as AlphaFold, is thanks to a database of protein structures dreamed up in the 1960s by Helen Berman go.nature.com/4hp4UCP
After thousands of microscope hours and several years of painstaking optimisation, @glynnca93 and I are very excited to share our latest manuscript. We outline our approach to investigate the molecular organisation within hippocampus tissue using cryo-ET.
I certainly have not the talent which some people possess of conversing easily with those I have never seen before.
imaging microtubule plus-ends in a zebrafish skin macrophage. always a treat to make the construct, inject, and go through the waiting period until i can image the adults and have it turn out like this! #microscopymonday #microtubulemonday #macrophagemonday
Largest brain map ever reveals fruit fly’s neurons in exquisite detail go.nature.com/4dx4qY7
Have you ever wanted to design protein binders with ease? Today we present 𝑩𝒊𝒏𝒅𝑪𝒓𝒂𝒇𝒕, a user-friendly and open-source pipeline that allows to anyone to create protein binders de novo with high experimental success rates. @befcorreia @sokrypton biorxiv.org/content/10.110…
Please check out our (@PDClab @bewersdorflab) latest work on determining the location of the lipid transfer protein VPS13B within the Golgi complex. We use 7-color #FLASHPAINT imaging to locate VPS13B within the Golgi complex. @JCellBiol @YaleMed doi.org/10.1083/jcb.20…
So, in the end, let’s go back to the original query, “Is fever good or bad? The short answer is: A little bit of fever is good, but a lot of fever is bad. We already knew that, but now we have a mechanism for why it's bad. 17/17 science.org/doi/10.1126/sc…
OptoTrap for endogenous protein clustering in Drosophila. COOL!! In vivo optogenetic manipulations of endogenous proteins reveal spatiotemporal roles of microtubule and kinesin in dendrite patterning | Science Advances science.org/doi/10.1126/sc…
Check out these SEM images of the external anatomy of larve, pupae, and adults. An anatomical atlas of Drosophila melanogaster—the wild-type academic.oup.com/genetics/artic…
.@lozwelch, Nadine Muschalik & Sean Munro @CellBiol_MRCLMB @MRC_LMB find that the FAM114A proteins are adaptors for the recycling of Golgi enzymes. #OpenAccess #ReadAndPublish Highlight: journals.biologists.com/jcs/article/13… Article: journals.biologists.com/jcs/article/13…
A short video on how our new Microtutor LIVE courses work. 😀 Applications for the first course are due next week! 🔬👩🏫microtutor.globalbioimaging.org @GlobalBioImage @cziscience #microtutor Please repost!
Today in @CellCellPress we report evidence for a covalent linkage between small RNAs and N-glycans via acp3U Work by @axe_xie @PeiyuanChai +collab w/@GarciaLabMS | @HSCRB Excited to accelerate more work related to glycoRNAs in many new contexts. doi.org/10.1016/j.cell…
"Jana Gana Mana" is the national anthem of India, originally composed in Bengali by poet Rabindranath Tagore, who was awarded the Nobel Prize in Literature in 1913. Pictured: An English translation of Jana Gana Mana by Tagore
having trouble tuning your gyroscope? check out this delightful first pape from Brad Dickerson's (@yelzebub) lab, led by @verbe_anna authors.elsevier.com/a/1jU9j3QW8S6F
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