@PellegriniLab Profile picture

Pellegrini Lab

@PellegriniLab

Structural Biology Lab in the Department of Biochemistry, University of Cambridge.

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Pellegrini Lab Reposted

Any Ph.D. students near the end of their thesis and not in Texas, looking to PostDoc in Texas? The Welch Foundation now provides fellowships. If you are interested in chromatin, HDX, or proteins in general... let's chat! welch1.org/grants-program…


Research Associate (Fixed Term) @Cambridge_Uni jobs.cam.ac.uk/job/41419/ Great job opportunity at @CamBiochem in the @PellegriniLab . If you're interested in molecular mechanisms of DNA repair and replication, please apply and join us. We're looking forward to your application! 🙂


Pellegrini Lab Reposted

Introducing CRISPRpedia – our new, free online textbook for everything CRISPR! Learn (& teach) about #CRISPR from its role in nature to development of the genome editing tool, to applications in research, medicine & agriculture. Check it out! innovativegenomics.org/crisprpedia/ #STEMEd

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We have a Senior Laboratory Technician available, together with the Luisi lab, here in Biochemistry, Cambridge, UK. Please apply at jobs.cam.ac.uk/job/31308/ or share with colleagues/friends. Deadline is October 6th. Looking forward to your application!


Pellegrini Lab Reposted

A postdoc opening for a biophysics/NMR/crystallography expert in our group to work on an exciting new drug target, to get early fragment data for inhibitor development process. jobs.cam.ac.uk/job/31237/ #XChem #FBDD #postdocjobs RT appreciated


Happy to share our latest preprint, on the interaction of the SARS-CoV-2 virulence factor nsp1 with our old friend Pol alpha-primase. Well done @mairikilkenny who kept going through lockdowns to complete this very nice piece of work. biorxiv.org/cgi/content/sh…


Pellegrini Lab Reposted

Today we introduce @PellegriniLab, Theme Lead in Molecules and Cells. Luca studies the structural and functional properties of proteins responsible for the maintenance and replication of our genome. Learn more about our #ResearchThemes: bio.cam.ac.uk #BiologicalSciences

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Check out our latest bioRxiv preprint on DNA repair factor CtIP: biorxiv.org/cgi/content/sh… Well done @Chris_Morton16 and thanks to Rob Rambo, Yuji Sasaki and Owen Davies for the great collaboration 🙂


Also a Research Assistant position: jobs.cam.ac.uk/job/28607/


3xpostdoc positions available in our lab, please spread the word! (or apply yourself 🙂) jobs.cam.ac.uk/job/28616/


Pellegrini Lab Reposted

Three PhD studentships to understand and manipulate interactions between disordered proteins and Aurora-A. Come and join a dream team of structural, chemical and cell biologists! phd.leeds.ac.uk/project/838-un…


Pellegrini Lab Reposted

Pisani Lab is looking for a post-doc! If you have experience in CRISPR-Cas9, retroviral/lentiviral infection, cell-cycle/apoptosis analysis, cell-survival and proliferation assays and also some biochemistry experience, please send an email to francesca.pisani@ibbc.cnr.it !


What's wrong with title?😉

Current status: trying to write Fuck Brexit into my ERC grant down the diagonal of the abstract. Non trivial.



A very enjoyable collaboration, thanks to all involved in unravelling the G-quadruplexy mystery... @MRC_LMB @CamBiochem @mairikilkenny

Julian Sale @MRC_LMB @PellegriniLab @CamBiochem show that G-#quadruplex binding and resolution by Timeless and #helicase #DDX11 allows eukaryotic replication through DNA secondary structures embopress.org/doi/10.15252/e…

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“What are we going to do today Brain?” “Same thing we do every day boys: TRY TO TAKE OVER THE WORLD!”

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Good luck to all going back to the lab tomorrow & great to be a family with the @HyvonenGroup Here's our back-to-work anthem: youtube.com/watch?v=uyGY2N…


Pellegrini Lab Reposted

During the lockdown I have mastered my watermelon cutting skills... Send me back to the bench before I go crazy 🍉 #watermelon 🔬#LabSick

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Check out our paper just out, on the human DNA replicative helicase CMG and its complexes: academic.oup.com/nar/advance-ar… Very pleased to see this out, and huge congratulations to Neil, it's a great achievement!


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