Omar Ali
@OmarrificBioPartner @ Awaken Capital…tweets my own on Belief, Biology, Basketball, Body Boards… ☪️🧬 🏀 🌊
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#FDA CBER's Marks apparently apologizing (!) for holding back in vivo #CRISPR development in the US: h/t @endpts
Vamos, @RafaelNadal! As you get ready to graduate from tennis, I’ve got a few things to share before I maybe get emotional. Let’s start with the obvious: you beat me—a lot. More than I managed to beat you. You challenged me in ways no one else could. On clay, it felt like I…
Upgraded my numbers for $NTLA for ATTR after seeing the data. With the data being better than Partisiran, I think I can give them a higher market share in comparison.
I went over the $NTLA press release, slide deck and the live and replay of the call. I can't find a single reason to dislike the data. Overall, it looks like clear and decisive best in class data with a one time therapy. Patients seem very eager from the responses about being…
My #1 issue with FDA is that it erects unnecessary barriers to innovation (e.g. two replicate phase 3 studies instead of one, refusal to accept valid clinical results from other nations, etc.). This stops patients from accessing promising therapies & raises prescription drug…
Today we report Evo, a generalist foundation model for biology, on the cover of @ScienceMagazine Trained on billions of DNA nucleotides, Evo was designed to capture two key aspects of biology: the multi-modality of the central dogma and the multi-scale nature of evolution.
A new Science study presents “Evo”—a machine learning model capable of decoding and designing DNA, RNA, and protein sequences, from molecular to genome scale, with unparalleled accuracy. Evo’s ability to predict, generate, and engineer entire genomic sequences could change the…
“I’m not a basketball coach, I’m a person who cares about other people” - Joe Mazzulla (Via @NBCSCeltics 🎥)
The United States is 4% of the world's population, and produces 70% of the world's pharma profits. We rank 60th in global life expectancy.
Day after cold analysis of $NTLA data in HAE. Clearly, a disappointment as we were all hoping this would be a functional cure. Its now about 80% effective. Does this stand against current commercial competitive therapies? It could. Compliance is a big issue in chronic…
Joe Mazzulla says he feels no pressure to maximize this #Celtics window. "We're all gonna be dead soon, and it really doesn't matter anymore, so there's 0 pressure." "It's not pressure, it's an opportunity."
Back in 2014, Novartis ditched its RNAi research, giving the lead scientist the first "courage award" for stopping bad projects!🤦♂️ Novartis ex-CEO Joseph Jimenez said at the time, "One of the reasons why spending in the pharmaceutical industry is so high is that many scientists…
Realize that what resulted from this was the bombing of a Catholic Church in Northern Lebanon. Apparently, Catholics are Hezbollah as well....
REPORT: Israel Preparing Large-Scale Attacks in Lebanon Following Hezbollah Strike on Military Base Prime Minister Netanyahu, speaking at the Golani base, declared, “We will continue to strike Hezbollah without mercy everywhere in Lebanon – including Beirut. Everything is…
💔Heartbreaking | Yesterday wasn't the first time Shaban cried out for the world's help as Israel burned him alive. He had been pleading for the world to save him because he was the sole provider for his family. Now, he's gone, leaving behind two sisters and a little brother with…
His name was Shaaban. He was loved by his family and friends, a memorizer of the Quran. He’s named after the month that in the Islamic tradition is referred to as the forgotten month. Let him never be forgotten.
De novo creation of an innate immune LPS receptor. Anh Cao identified the principles of LPS detection by caspase-11, revealing the CARD as a bipartite lipid binding module. This knowledge allowed us to convert an ancient CARD-like protein into a functional LPS receptor.
Scientists often aim to tackle the world’s most complex problems. However, what I’ve learned throughout my career is that complexity tends to scare investors away, and these solutions rarely reach patients.
Take a moment and watch this video. Then watch it again every day. So much truth in 45 seconds. Purpose.
Excellent chemistry meme. I hope it goes chiral!
Mohammed Qahtani won the Toastmasters World Championship of Public Speaking. It’s easy to see why. Please watch his speech. Words have power. Words can unite or divide. Words can spit venom or can mend a broken soul. Words absolutely matter.
United States Trends
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