MichaelMcMurraylab
@McMurraylab@mcmurraylab.bsky.social Official account of Michael McMurray’s lab in the Dept. Cell and Developmental Biology
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We are still recruiting postdoctoral fellows! We are looking for individuals interested in human pathogens and their response to antifungals. An NIH R01 fully funds this project. This project involves genetic, cell biology, microscopy, and proteomics approaches! Please RT 🙏🏽
🚨Open Postdoctoral Associate Position🚨 Our lab is currently looking for a postdoctoral fellow to study how Aspergillus fumigatus septins contribute to response to anti-cell wall drugs. careers.pageuppeople.com/968/cw/en-us/j…
Sadly, your email does NOT find me "impelled by a fervent scientific curiosity in the field of Plant Biology" hence I'm afraid I will not "avail this opportunity to share [my] scientific excellences" but I salute your farraginous lexicon 😄😄 (no disrespect to plant biologists)
Ok, a second paper accepted in the same week is helping a bit, I must admit 😐
News that our paper was accepted today somehow doesn't bring the same sense of satisfaction or joy...
News that our paper was accepted today somehow doesn't bring the same sense of satisfaction or joy...
A trove of insights! I found an ArgPro dicodon exactly where we’d predict to drive pausing in Cdc12, the septin we think is slowly translated, in a loop where the α2 helix would be exiting the ribosome & closing the α-β sandwich where other Frydman lab data showed chaperones bind
1. Check out our MS just out! Amazing Mauricio Aguilar developed a new ML pipeline that identifies ribosome pausing sites as an Anomaly Detection problem to overcome spurious signals that arise when analyzing RiboSeq data. science.org/doi/10.1126/sc…
🚨 Great alternatives to BioRender are now available!! 📢 @NIAIDNews offers a collection of public figures and icons for everyone to use. Check it out at bioart.niaid.nih.gov
1. Check out our MS just out! Amazing Mauricio Aguilar developed a new ML pipeline that identifies ribosome pausing sites as an Anomaly Detection problem to overcome spurious signals that arise when analyzing RiboSeq data. science.org/doi/10.1126/sc…
Register here: meetings.embo.org/event/25-clima… for the 13-16 April 2025 Lisbon. Please join us!
I was an ableist asshole when I first became a teacher. Because that’s what I was taught! In my defense, academic institutions told me a strict attendance policy was required. What changed my perspective & my assessment criteria? Disabled students 🧵
MBoC Call for Papers on Evolutionary #CellBiology. Submit an article by Dec 30 to lead editors: @Dey_Gautam, @EMBL @McMurraylab, @CUAnschutz @mcmomany, @universityofga @onishilab, @DukeU @C_M_Schroeder, @UTSWNews @HVGoodson, @NotreDame Submit: molbiolcell.org/evolutionary-c…
Yay, #SEPTforSEPTINS is here again!
Happy #SEPTforSEPTINS 286 days left for #FASEBSeptin2025 SEPT1 is for Septin 1, a gene in the mouse locus 16p11.2, the microduplication of which induces obesity with defects in lipid droplet and triglyceride metabolism pubmed.ncbi.nlm.nih.gov/35072981/
I was reminded that most proteasomes reside in the nucleus and I was like, "How did I forget that?" and then I was like, "Because it's basically never shown in any figure about the proteasome"! Are cytoplasmic proteasome substrates imported into the nucleus for degradation? 🧐
Just submitted my 26th manuscript peer review of 2024. That's one every <10 days. I think I am going to take a little break now...
McMurray lab and @CSD_CUAMC graduate/alumnus making us all very proud 👇🏽👇🏽👇🏽
Happy #SEPTforSEPTINS 286 days left for #FASEBSeptin2025 SEPT1 is for Septin 1, a gene in the mouse locus 16p11.2, the microduplication of which induces obesity with defects in lipid droplet and triglyceride metabolism pubmed.ncbi.nlm.nih.gov/35072981/
Beautiful work! fits so nicely with our 2022 study of a yeast septin protein that appears to stall during heterologous E. coli translation when GroEL is missing (PMID 35947497)
New from our lab @TheCrick , led by @BetkaRoe A fun side project that tried to understand what happens when a chaperonin encounters a translating ribosome. biorxiv.org/content/10.110…
🚨Does your research combine evolution and cell biology? If so, submit an abstract to our subgroup session “Evolutionary Cell Biology” at this year’s ASCB meeting #cellbio2024! Deadline is in 1 week. Co-organizers are @HVGoodson @mcmomany @McMurraylab @onishilab
Just thinking about how communicating about science is not an exact science 😆
One mutation is lethal; a second mutation acts as a suppressor to restore viability. Complete this sentence: The effect of Mutation 2 is to rescue the
Beyond thrilled and proud to have this work out! What a labor of love and learning. @cellbioMichael was (his usual) amazing! Very grateful to precious collaborators Mike Staddon and Shila Banerjee. See link for non-blurry Graphical Abstract, the Dispatch, and the COVER!
Lovely work from Michael Werner, colleagues in the @AmyShaubMaddox lab and biophysics collaborators revealing how pulses of Rho activity interact with mechanical feedback to mediate furrow ingression in cytokinesis 1/2 sciencedirect.com/science/articl…
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