@LiaVLChappell Profile picture

Lia Chappell

@LiaVLChappell

Molecular biologist and sequencing tech geek. Fan of single cell genomics. She/her.

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Pinned

Manuscript now live! We used a new PCR-free RNA-seq protocol to better understand the most AT-rich parts of the human malaria parasite P. falciparum. Collaboration between Sanger @rayner_julian @Berriman_mb4 @BiottofnI and PSU @LlinasLab @philippzross biorxiv.org/content/10.110…


Lia Chappell Reposted

Two days remaining to apply for a Postdoc in my team exploring somatic mutational landscapes across primate species. The position is based @GeneticsCam and will involve collaboration with @sangerinstitute and @UCBerkeley

🦍Postdoc in Somatic Evolutionary Genomics🦍 Join my team @GeneticsCam on a pioneering project mapping somatic mutations across primates! 🌍Collaborate with experts @UCBerkeley & @sangerinstitute 🔍Experience in genomics? Apply by Nov 16! Details: jobs.cam.ac.uk/job/48757/

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Lia Chappell Reposted

Fascinating insights into the male germline from my beloved labmate @MDC_Neville and PhD supervisor @R_Rahbari 🚀. A must-read for those following genetic & reproductive science! 👀

Excited to share our new preprint in which we address: (1) Accurate sequencing of sperm at scale (2) Positive selection of spermatogenesis driver mutations across the exome (3) Offspring disease risks from male reproductive aging [1/15] medrxiv.org/content/10.110…



Lia Chappell Reposted

You were warned, check out the latest pre-print from @MDC_Neville and @R_Rahbari Check out for some super cool insights on the potential consequences of the male germline ageing!

Excited to share our new preprint in which we address: (1) Accurate sequencing of sperm at scale (2) Positive selection of spermatogenesis driver mutations across the exome (3) Offspring disease risks from male reproductive aging [1/15] medrxiv.org/content/10.110…



Lia Chappell Reposted

II'm excited to finally share our study on the mutational landscape and selection dynamics in sperm, now live on medRxiv: medrxiv.org/content/10.110…. We explored how positive selection impacts mutation rates, especially with age. Here’s a quick thread on our findings! 🧵👇


Lia Chappell Reposted

Excited to share our new preprint in which we address: (1) Accurate sequencing of sperm at scale (2) Positive selection of spermatogenesis driver mutations across the exome (3) Offspring disease risks from male reproductive aging [1/15] medrxiv.org/content/10.110…


Lia Chappell Reposted

My old account has disappeared, and I'm not sure why. I’m hoping to recover it somehow or link it to my new one! Thank you to everyone for reconnecting!


Lia Chappell Reposted

Congrats to @RebecaOLE_ and Andrew Waters for delivering this one. Thanks also to the patients and our team collaborators including @clare__turnbull and Maria Jasin/MSKCC. High-resolution functional mapping of RAD51C by saturation genome editing: Cell cell.com/cell/fulltext/…


Lia Chappell Reposted

A full size @illumina NovaSeq 6000 in @LEGO_Group seem at #ESMO2024 @myESMO It even has Lego flowcells.

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Lia Chappell Reposted

And it's a wrap for #SingleCellRio2024! @BoroniMariana gives a great closing speech for this conference, with 100 participants from across Latin America and more! 🇧🇷🇲🇽🇨🇷🇺🇾🇻🇪🇦🇷🇵🇪🇨🇱🇨🇴 Thanks to all organisers for a great symposium 😀

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There's so much cool science going on here at the #SingleCellRio2024 symposium - see @daniela_oaks tweets for lots of awesome people to follow here!

We are starting the #SingleCellRio2024 symposium in Rio de Janeiro 🇧🇷! This conference will bring together people interested in #singlecell research across Latin America! Sponsored by @eventsWCS @czi, looking forward to exciting science for the next two days!

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Lia Chappell Reposted

Super happy to be part of the training team in the Single Cell Genomics course this year, in Rio de Janeiro 😍 Working together towards a single cell community in Latin America & the Caribbean 🧬💫 #SingleCellRio24 @eventsWCS @PatriciaPossik @David_J_Adams & many others!

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Lia Chappell Reposted

Single cell oncology team #SingleCellRio24

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Lia Chappell Reposted

Thrilled to be here with this amazing community! #SingleCellRio24

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Lia Chappell Reposted

For the first keynote talk #SingleCellRio2024, @MoriLabe @unicampoficial 🇧🇷 is telling us about macrophage subpopulations associated with #metabolic disease discovered through single cell analysis - first Latin American team funded by @czi 🤩

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Lia Chappell Reposted

No better way to spend my birthday🎂; Copacabana... Caipirinhas... and SINGLE CELLS!🇧🇷Had the pleasure to be part of the LATAM single cell courses, & this year it includes a 2-day symposium bringing together the LATAM #singlecell community #SingleCellRio24 …erences.wellcomeconnectingscience.org/event/single-c…

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Lia Chappell Reposted

This 👇 - the power of ⁦@ConnectingSci⁩ together with ⁦@cziscience⁩ to bring together 100 scientists from across LATAM to talk about single cell sequencing #SingleCellRio24

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Lia Chappell Reposted

One of the great outcomes for #singlecellrio23 was this single cell oncology work group we assembled, with both students and instructors 💪

Single cell oncology team #SingleCellRio24

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