Joni Coleman
@Joni_ColemanSenior Lecturer in Statistical Genetics @KingsIoPPN. Serial Twitter-breaker. Group GitHub: https://t.co/VVb0z3QjqV… . Views own. He/Him
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ANNOUNCEMENT: I am retiring this account, and it will be deleted in 2025. Come join me at Bluesky: jonicoleman.bsky.social
Thank you Pradeep for your support and advice for this project🙏😃 We’re thrilled to introduce DiscoDivas, a new method designed to generate Polygenic Risk Scores (PRS) for diverse espcially admixed populations 1/
Current polygenic risk scores require binning of ancestry groups but we know ancestry is a continuum. Our study led by @Yunfeng_Ruan introduces DiscoDivas, a new generalizable PRS framework across the ancestry spectrum medrxiv.org/content/10.110… @medrxivpreprint @PRSdiversity
🚨 Preprint 🚨 SSRI #antidepressant users report on whether drugs ‘helped’ them. In @uk_biobank’s 2nd Mental Health Q, - 20k respondents reported on - 4 SSRI antidepressants, answering ‘yes’ or ‘no’ to whether specific drugs helped What do these reports capture? 1/7
Agreed! That's why I wrote ggpubfigs, a ggplot2 extension that *only colorblind-friendly color palettes. Easily make your figures colorblind-friendly with ggpubfigs! x.com/NKWhiteman/sta…
A reminder that your search committee chair, grant proposal reviewers, and manuscript reviewers might be among the 1/12 XY or 1/200 XX who can’t see what you think is obvious in your figures because they have a color vision deficiency. Adobe tools, many papers on the topic, etc.
I want to try something new at #ASHG24 this year: I'm going to block some time on Friday afternoon to meet with any trainees who would be interested to chat on any topic.
The @SGDPCentreKCL is participating in #Movember this year to raise funds and awareness for initiatives that support men's mental health issues and suicide prevention. Sponsor our team here shorturl.at/tdlmy
I know this is a funny satire, but there is no reason you would see variation on the Y particularly, there would be a considerable risk of rare event bias, and this would be brutally underpowered.
Having referred to it a few times this week, here is a (IMO) slightly more user friendly derivation of the LD-score regression estimator of heritability and its assumptions: gusevlab.org/projects/hsq/l…
Do you want to know what are the consequences of splicing QTLs at the transcript level? Check out the tutorial of our new @ELIXIREstonia eQTL Catalogue Browser visualisation tool: youtube.com/watch?v=qS8coZ…
Excited to share our latest manuscript in @NatureGenet! Utilizing high-resolution genetic data imputed with a population-matched reference panel, we uncovered causal genetic variants for a wide range of human traits over 200K participants from Japan (1/20) nature.com/articles/s4158…
If you're not following the Behavior Genetics Association account yet (@BehaviorGenetic), please do! 🧬🧠🤸🏽 Me and @margotvdweijer will be running it for the time being, sharing BGA updates and summaries of interesting research from their classic journal 📜 RTs appreciated! 🙏🏽
.@Joni_Coleman & I are looking for a bioinformatics/genetics PhD student in this joint MRC industry PhD scheme "Unveiling Disease-Causing DNA Repeats with Long-Read Sequencing" - a 4 year PhD funded by @nanopore & @The_MRC iCASE scheme. kcl-mrcdtp.com/project/unveil…… #MRCDTP25
As ever, we're keen to hear from ANYONE for either of these opportunities — all and every identity and combination thereof is encouraged to apply. Message me here, on @Joni_Coleman, or via contact details in the adverts with any questions! 5/5
@thaliaeley and I are recruiting a student to examine gene-environmental influences on anxiety and stress disorders. Come help us understand how genetic influences work! This is an @KCL_MRCDTP Core project, funded by @The_MRC Details here: kcl-mrcdtp.com/project/unders… 4/5
@psychgenomics & I are recruiting a student to develop short tandem repeat variant calling from long-read genome sequence data, in collaboration with @nanopore This is a @KCL_MRCDTP iCase project, co-funded by @The_MRC Details: kcl-mrcdtp.com/project/unveil… #MRCDTP25 2/5
But wait - there's more! 🚨PHD ALERT #2🚨 Are you another enthusiastic person looking for a PhD starting in Oct 2025? Do you have a undergraduate degree in genetics, psych, stats, or similar? You too can join our lab at @SGDPCentreKCL @KingsIoPPN @KingsCollegeLon! 3/5
🚨PHD ALERT #1🚨 Are you an enthusiastic person looking for a PhD starting in Oct 2025? Do you have a undergraduate degree in statistics, computer science, biology, or similar? Come and join our lab at @SGDPCentreKCL @KingsIoPPN @KingsCollegeLon! 1/5
An opportunity to join a fantastic group here at KCL — very happy to talk to anyone who wants a view of life and research here!
Postdoctoral role in statistical genetics at @NIHRMaudsleyBRC & @SGDPCentreKCL Research in genetics and polygenic scores, to advance care for mental disorders. Collaborative projects, good for a new PhD with comp. & stat skills. Please RT! kcl.ac.uk/jobs/095205-po…
We’re fast approaching our #GLADiversary, celebrating 6 years of the GLAD Study There’s never been a better time to recap our achievements, our plans and of course, share our thanks to you, our participants for your continued support Keep an eye out for our upcoming posts…
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Gerome Breen
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Dr Cathryn Lewis
@cathrynlewis -
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@SGDPCentreKCL -
Prof Thalia Eley 💙
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Alex Strudwick Young
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Dr. Ziada Ayorech (she/her) 🌈
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