Jeffrey Cloutier, MD, PhD
@JCloutierMDDermatopathologist, Bone / Soft Tissue Pathologist. Assistant Professor of Pathology at Dartmouth Geisel School of Medicine.
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We’ve long known that epithelioid #sarcoma can be divided into proximal and classic subtypes, which have distinct clinical and morphologic features. Now, a new study by Sigalotti et al. gives us molecular insight behind these subtypes. Fascinating work! sciencedirect.com/science/articl…
One of my favorite 40x fields I've ever seen! Beautiful ladybird cells (neoplastic cells with a cytoplasmic rim of hemosiderin) in a tenosyonvial giant cell tumor. #BSTpath
A deep dive into SFT epigenetics reveals site-specific DNA methylation patterns, highlighting possible markers for distinguishing primary vs. metastatic tumors. Read more: sciencedirect.com/science/articl… #BSTpath #sarcoma
The diagnosis for this well-demarcated, recurrent subcutaneous mass with unusual clear cell features and chondroid differentiation remained a mystery until #molpath correlation: Ossifying fibromyxoid tumor Unusual patterns described in this #BSTPath #dermpath collaboration
Our new work in Virchows Archiv #pathology #dermatology #dermpath #BSTpath link.springer.com/article/10.100…
Spitz nevi with 11p gains are histologically distinctive, typically intradermal with pronounced desmoplastic stroma, an infiltrative growth pattern, and pleomorphic nuclei. Activating HRAS mutations with secondary 11p gain likely drive their unique appearance. #dermpath
ST mass, inguinal. KRT+/loss of INI. Nice example of proximal-type
A great opportunity!
A stunning example of hybrid SEF/LGFMS. MUC4 = diffusely positive. Most cases harbor FUS::CREB3L2 fusions, similar to that seen in most LGFMS. #BSTpath #Sarcoma
Validation and Implementation of a Somatic only Tumor Exome for Routine Clinical Application. From @AMPath members at @DHMCandClinics and @DartmouthHealth @LJTafeMD @gtsonga Full #OpenAccess text: jmdjournal.org/article/S1525-…
Congrats, Paige! 👏🏼 This is definitely a standout case of HFLT! Full text here ⬇️ onlinelibrary.wiley.com/share/author/H… #BSTpath
Congrats to our senior resident Paige and our attending @JCloutierMD ! onlinelibrary.wiley.com/doi/10.1111/hi… #DHPathRes 🎉🎉🎉
Never skip “leg day”! Adding this to the recommended reading list for the #BSTPath rotation immediately. Congrats, @Nooshin_Dashti @ScottBikeethan and team. #PathTwitter @DHPathRes
Focusing only on tumors is like the guys who lift weights at the gym and only focuses on the upper body with no dedicated leg days! If you focus more on legs (and core) the upper body will follow.
Join us for the Virtual Open House! Thursday September 5th, 6-7 PM EST. More information about our program click: gme.dartmouth-hitchcock.org/pathology/prog… #DHPathRes #Match2025 #pathmatch25 #pathmatch2025 #pathmatch
Desmin immunostain highlighting cells with striking dendritic morphology in TGCT. (PMIDs 9796719, 10757395) 🕷️ #BSTpath
TRPS1 - widely known as a marker of breast carcinoma - is also expressed in MPNST, particularly those with PRC2 inactivation. Check it out ⬇️ kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2… #BSTpath
Check out our latest report on juvenile trabecular ossifying fibroma. Our data suggests that SATB2 inactivation plays a significant role in the oncogenesis of a subset of these tumors. Read the full study for free: onlinelibrary.wiley.com/share/author/D… #SATB2 #BSTpath #ENTpath
⚫SYNOVIAL CHONDROMATOSIS: a locally aggressive synovial tumor. Imaging shows multiple intraarticular nodules of similar size. Histology illustrates synovium-lined cartilaginous nodules with clustered chondrocytes. Nuclear atypia lacks prognostic significance. #BSTpath #Radpath
Excellent talk today on ancillary tests in melanocytic lesions by my amazing colleague Dr. Shaofeng Yan! @MGHPathology @DHPathRes #dermpath #melanoma #bimt
Started with palmar erythema and ended with optic nerve involvement. Surprised by the number given the overall inflammation on routine. What is it? 🔬
youtu.be/MX6aJ00MAdA Join Dr. Lisa Zhang from Massachusetts General Hospital as she interviews leading pathology experts, Dr. Sarah Dry, Chair of Pathology at UCLA, and Dr. Laura Collins, Vice Chair of Pathology at Beth Israel Deaconess Medical Center and Harvard Medical…
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