Borad Lab
@BoradLabThe BoradLab is focused on development of novel therapeutics for liver, biliary and pancreatic cancer. Tweets own, not that of employer.
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Congrats to Dr. Mansi Arora (@Mansi54948915 ) from @BoradLab for her work showing lack of superiority of NUC-1031 to gemcitabine in pre-clinical models of biliary tract cancer. link.springer.com/article/10.100…
Non-alcoholic steatohepatitis (#NASH) is associated with reduced expression and activity of urea cycle enzymes, resulting in hyperammonemia bit.ly/2MVtsUW #fattyliver #NAFLD @jsgracia @RajivJalan1 @ucl @AUHdk
Congrats to Dr. Daniel Ahn from @Boradlab for receiving an ALLIANCE Scholar Award for his proposal using CDK inhibitors in Biliary Tract Cancers !
Dr. Marius Nagalo and @MiteshBorad from @BoradLab kicking off things at pre-meeting get together with @LewisRobertsMD, Dr. Gallardo from Chile and Dr. Somda from Burkina Faso. International collaboration !
Cancers of the liver, pancreas and biliary tract (HPB Cancers) are amongst those with the highest unmet need.
Congrats to Kais Zakharia for his recent publication on CK2 inhibitor CX-4945 in #Cholangiocarcinoma. Clinical trial led by @MiteshBorad from @BoradLab underway (clinicaltrials.gov/ct2/show/NCT02… …). ncbi.nlm.nih.gov/pubmed/30316146
Congrats to @JM_Bogenberger from @BoradLab for his work on genomic profiling of biliary tract cancers. nature.com/articles/s4169…
@MiteshBorad from @BoradLab with hepatobiliary legend Dr. Henri Bismuth from France - renowned for Bismuth-Corlette classification of #Cholangiocarcinoma and split liver transplant among many other achievements.
An American treasure.
The #NIH Clinical Center in Bethesda, Maryland, is the largest hospital in the world devoted to clinical research and a resource for patients with rare diseases. @NCIResearchCtr
Requirements for effective #Immunotherapy Prime --> Expand --> Facilitate Function in TME.
Fun fact: Mariano discovered NTRK fusions too, while junior scientist working for @theNCI in the 1980’s. Someday, we WILL figure out how to drug RAS, but in meantime, MB’s work has led to some very promising NTRK inhibitors for advanced childhood and adult cancers.
Cool to hear legend Mariano Barbacid @CNIO_Cancer, co-discoverer of #ras oncogenes, talk about circumventing #kras’s “undruggability” in #pancreaticcancer #AACRPanCa18
Implementing #Genome-Driven #Oncology -> Baselga and cols make the leap goo.gl/UjTEkH #cancer @sloan_kettering
Biomarker fun fact: the original biomarker: Bence Jones protein, identified 1846. #CBCIII
@JM_Bogenberger from @boradlab presenting his work on Napi2b and HER2 ADCs at Individualizing Medicine Conference 2018
@MiteshBorad from @BoradLab will be speaking @ASU @evmedasu Center for Evolutionary Medicine (CEM) Seminar Series, highlighting work on Precision Medicine, Gene Therapy and Oncolytic Viruses on Sept 27, 2018. asuevents.asu.edu/content/cem-se…
Recent work from the Segatto Lab and @BoradLab showing the synergy between FGFR inhibitors and Heat Shock Protein (Hsp90) inhibitors in #cholangiocarcinoma. aasldpubs.onlinelibrary.wiley.com/doi/abs/10.100…
Congrats to Thomas Deleon, MD from @BoradLab for his work depicting Novel Immunotherapeutic Strategies in Hepatobiliary Cancers ! futuremedicine.com/doi/abs/10.221…
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