Allysson Allan
@AllyssonAllanVisiting Professor / CTO and co-founder at @genietechbio
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I must say, rumors of #ScienceTwitter's demise have been greatly exaggerated. Almost without fail, when I get a Google Scholar alert about a paper, I already saw it on Twitter a day or two earlier. To all the incredible scientists on here- please stay! You're making an impact.
Vote is cast. Nothing to do but wait. On to Denver for #ASHG24 … catching up with new science and old friends. I’m #hiring. Keen to make new friends interested in relocating to the NY area to develop tools and methods to help human genetics scale. DM me. 1/3
A great recap of all seasons from the "Denisova-Modern Human" romance series by @Linda_Ongaro and @emiliahsc doi.org/10.1038/s41588…
What does it mean to be Latin American? I don't know. The term spans so many cultures and identities that defining a single concept feels impossible. Today, our article on one aspect of Latin American diversity (genetics) was published in Cell Genomics. cell.com/cell-genomics/…
Generative Haplotype Prediction Outperforms Statistical Methods for Small Variant Detection in NGS Data academic.oup.com/bioinformatics… 🧬🖥️ github.com/ARUP-NGS/jenev…
TED: The Encyclopedia of Domains now published in @ScienceMagazine discovering and annotating 314 MILLION protein domains in the AlphaFold database. joint work of @CATH_Gene3D and @psipred here at UCL.
This is great! @NIAIDNews have launched a collection of public domain illustrations (currently 550 individual icons) bioart.niaid.nih.gov
After reading this new Family GWAS paper, I will never look at genetic correlations the same way again. Here are the genetic correlations for Cognitive Performance calculated from Family GWAS shown side by side with genetic correlations calculated from standard GWAS. First, note…
It took me SEVEN years to figure out that you can save a ggplot as a vectorized .svg file ggsave("file.svg"). The svg file can be opened on powerpoint and it will be completely vectorized, even text are still recognized as text boxes! No more recreating plots on illustrator!!!!!
Anaconda is "positing"...
I love stories like this When the results of a new drug that prevented 100% of HIV cases were announced at the 2024 AIDS conference, the room burst into spontaneous applause
Really excited to work with the EvolutionaryScale team, @alexrives @TomSercu @salcandido and so many more to accelerate the very frontier of generative biology. Also congrats to all our awesome partners for their work with the ES team! blogs.nvidia.com/blog/evolution…
This thread is crucial to delve into GPT-4 convolutions.
How many academic papers are written with the help of ChatGPT? To answer this question, we analyzed 14mln PubMed abstracts from 2010 to 2024 and looked for excess words: ** Delving into ChatGPT usage in academic writing through excess vocabulary ** arxiv.org/abs/2406.07016 1/11
The human chromosomes are numbered incorrectly (The fourth in an irregular series of threads about #Bioinformatics.) As most people know, 22 of our chromosomes are numbered from longest to shortest, plus we have X and Y... 1/6
Today, RGC has published an important paper in @Nature today, describing an analysis of close to a million human exomes (n=983,578) as a single variant call set (!). This is the largest and most diverse rare variant database created so far. This impressive feat is accomplished by…
In a collaboration between @M_Chintalapati ,@SkovLaurits , Alba Bosoms Mesa, @MatejaHajdi , @benmpeter and @moorjani_priya , we've journeyed into our shared history with Neandertals by analyzing over 300 genomes spanning 50,000 years. A thread 🧵🧬 biorxiv.org/content/10.110…
Check out this R Shiny App designed to explore causality and multiple regression: pitt.shinyapps.io/Rottman_Causal… This tool helps you understand possible relationships between variables, including noise, confusion, alternative effects, mediation, and interaction/moderation. A very nice…
Genes commonly express multiple #RNA isoforms. But how to visualise each isoform, how they differ in exonic structure and protein domains, as well as their expression levels from your RNA-seq data? Excited to introduce IsoVis isomix.org/isovis/ doi.org/10.1093/nar/gk… 1/n
The emerging role of tandem repeats in complex traits go.nature.com/3QC0X1z #Comment by Michael Lamkin & @mgymrek @UCSanDiego @ucsd_cse
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