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@SubangstromLLC
@TzuJingYang
@Chi_Wang2122
Join us on November 1 to celebrate the arrival of cryo-EM in Newark! Together with @AlexWeiSpotiton and @NeiditchLabRU, we are hosting the inaugural NJMS Cryo-EM Symposium @Rutgers_NJMS @rutgershealth . Registration is available via the following link: njms.rutgers.edu/research/sympo…
Wow! Cold FEG + Falcon 4 + RELION = 1.22 Å of apoferritin. Great for #CFAR, but what's more impressive is the reconstruction of β3 GABAA receptor with regions resolved to ~1.6 Å! Congrats @SjorsScheres & colleagues! What a day for the #cryoEM community biorxiv.org/content/10.110…
It’s the 2nd day of May, but have 2 days, 2 weeks or 2 months passed? Wondering how to keep track of time? Let SEMC help you count days one micrograph at a time through #microscopy Download the full #SEM Calendar through our new #science outreach page: nccat.nysbc.org/activities/ncc…
Nice
Here the Spotiton team shows their recent developments and successes at mixing specimen on the grid while simultaneously plunging rapidly: biorxiv.org/content/10.110… @VenkataDandey @AlexWeiSpotiton @edward_eng @SEMC_NYSBC
Keep up the good work. 👍
The NIH sponsored service centers are supporting efforts to combat COVID-19. At no cost the national #cryoEM centers are offering expedited review & fast track scheduling of instrument time for COVID-19 proposals. @NIH_CommonFund #cryoEM : @SLAClab #S2C2 @NCCATinfo @CryoEM_PNCC
Topaz v0.2.3 is out! Thanks to all the testers and developers who helped get Topaz to where it is today. The update adds the general denoising models in the Topaz-Denoise preprint, a pre-trained picking model, & an updated GUI. cb.csail.mit.edu/cb/topaz/ emgweb.nysbc.org/topaz.html
We present our Topaz-Denoise paper on general denoising models for cryoEM. We show 1) Small/low density views may be identified, 2) Shorter exposures may be used, increasing throughput, 3) Protein fragments/contamination are differentiated from background biorxiv.org/content/10.110…
We are seeking two researchers for 𝘪𝘯 𝘴𝘪𝘵𝘶 structural cell biology, including working hands-on with cryo-FIB/SEM, cryo-CLEM, cryo-ET, automation, and computational methods. Let us know if you are interested in 𝙝𝙖𝙫𝙞𝙣𝙜 𝙛𝙪𝙣 with us!
Our first @CryoEM_PNCC Open House will be occurring on August 8th, 2019 at 5:30pm until 7pm in Robinson Life Science Building, Portland OR. We will be picking guests up from the "PNCC Meeting Point" every 15 mins. See you there!
For the folks attending M&M 2019 in Portland the next days, please check out my fantastic colleague Felix Weis’ talk on Monday at 2PM, B110, on how we run our cryo-EM platform @embl Please RT! #MM2019Portland
Going to #MM2019Portland & ready to learn about the @NIH_CommonFund Transformative High Resolution #cryoEM program? Meet us at: 1) Short Course X-10 B110-111 Sun Aug 4 8:30A 2) X30.1-Tech Forum B117 Wed Aug 7 10:30A 3) Booth 652 by @CryoEM_PNCC with @SLAClab #S2C2 & @NCCATinfo
Where’s Ed at #MM2019Portland contest: Find me, talk about NIH #cryoEM programs & get a timed prize*. Sa/Su: I <3 NY hat/T-shirt M: Chameleon plushie (exhibit hall only) T: I <3 NY hoodie W: NCCAT T-shirt Th: mini plushie (*no cost, 1 ea, unclaimed prizes forwarded to next day)
The NIH #cryoEM national service centers focus on: 1) collecting high resolution data and 2) increasing users of cryoEM by cross-training laboratories established in other fields. Engage with us at #MM2019Portland to see how we can help advance biomedical research together.
Cool
Unpacking our Chameleon (a next generation sample prep instrument for cryo-EM, which is based on Bridget Carragher's "Spotiton"). Thanks to HHMI's 2019 Transformative Technology Competition. Can't wait to try it out!
We present Topaz Denoiser, a method for denoising cryoEM images based on Noise2Noise. A pre-trained model that takes only a few seconds to denoise an image on a GPU is included, or you can train your own model. Topaz v0.2.1 is available for free here: github.com/tbepler/topaz
Cryo-FIB/SEM Opportunity for people in the NYC and surrounding areas: Contact me or @bcarra2 if you would like to become a major user of a Zeiss Crossbeam cryo-FIB/SEM. Please send a description of your potential biological project(s).
Well deserved, Congrats!
Congrats to my PhD advisor Bridget Carragher @bcarra2, recipient of the distinguished scientist award from the microscopy society! So well-deserved! Also congrats to Alex Noble @alexjamesnoble on the Palade award - @SEMC_NYSBC is on fire!! 🔥🔥🔥
Protein denaturation at the air-water interface and how to prevent it dx.doi.org/10.7554/eLife.…
Congratulations to Gabe @LanderLab for winning the @ProteinSociety Young Investigator Award!
FRESH OFF THE PRESS: The Protein Society Symposium #PS33 2019 Award Winners Announced! #proteinsociety eurekalert.org/e/937J via @ProteinSociety @EurekAlert
We release a Topaz GUI and several updates: github.com/tbepler/topaz Topaz is a novel deep learning particle picker that can pick any shape & size particle, e.g. all orientations of the particles in the logo. The GUI works on modern web browsers; test here: emgweb.nysbc.org/topaz.html
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