Anu Suomalainen-Wartiovaara Lab
@ASW_labMission: Understand the molecular background of mitochondrial disorders to develop diagnosis and therapy. (managed by lab members) @STEMMprogram @helsinkiuni
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@AWartiovaara
@LabPrudent
@mitopinionated
@pirinenlab
@MetaStem_Center
@_CVasilescu
@OtonkoskiT
@LabKauppi
@KatajistoLab
@WredenbergLab
@JuhaKlefstrom
@HTyynismaa
@fumi_suomi
@Kivela_lab
@FhrcGracile
Time for a short explicative 🧵 for the busy 🐝! In our new report (#OA: rdcu.be/dTXcm) we found that enhancing #mtDNA replication can be deleterious for newborn #heart, causing dilated #cardiomyopathy & #ferroptosis 🫀 (1/6)
My last #PhD project out in @NatureComms, and first paper as co-corresponding author 🤓 Summary thread coming soon 📜 Massive thanks to the incomparable @AWartiovaara @seminerkul @JMitophile @Kivela_lab @WickstromLab and all other contributors!
ASWlab's Rohit Verma & @marmyleva_ana together with @Elstar4stars talk about #mito in research and patient care in @SciBasementPod podcast episode: open.spotify.com/episode/3JvdPR… #lightupformito
The PolG Foundation supports mitochondrial disease research. The Foundation's short film describes how the disease affects the lives of patients and their families. The PolG Foundation Film youtu.be/Oh-a_EKgp_Y?si… via @YouTube
PolG Foundation tukee mitokondriosairauksien tutkimusta. Säätiön lyhytfilmi kuvaa koskettavasti kuinka sairaus vaikuttaa potilaisiin ja heidän läheisiinsä. (Video vain englanniksi) The PolG Foundation Film youtu.be/Oh-a_EKgp_Y?si… via @YouTube
Fantastic work and exciting findings by @jclandoni and @ASW_lab👇
High mtDNA replication frequency is deleterious for newborn heart, causing dilated cardiomyopathy & ferroptosis. Our paper out in @NatureComms, outstanding work by @jclandoni Thanks for crucial results @seminerkul @ASW_lab @HelsinkiUniMed @helsinkiuni nature.com/articles/s4146…
High mtDNA replication frequency is deleterious for newborn heart, causing dilated cardiomyopathy & ferroptosis. Our paper out in @NatureComms, outstanding work by @jclandoni Thanks for crucial results @seminerkul @ASW_lab @HelsinkiUniMed @helsinkiuni nature.com/articles/s4146…
Very happy to share our new article of the interaction of mitochondria, innate immunity and viral infections and the relevance for brain &liver disease. Impressive work by @KangYilin Thanks @hepojoki @Olli_Vapalahti and all collabs! @helsinkiuni @ASW_lab rdcu.be/dDx2G
Metabolism Seminar time again next week March 26th at 9-11 in Biomedicum. Exciting talks from @OorniLab and @ASW_lab on lipoproteins, atherosclerosis, mitochondrial disease and mtDNA replication ☕️🍪at 8:30,Welcome! @HelsinkiUniMed @STEMMProgram @LifeSciHelsinki @HiLIFE_helsinki
Thank you JCB for selecting our article on metabolic ciliopathy of astrocytes as one of the 10 highlights of 2023 in the journal’s special issue ”Year in Cell Biology” @ignatenkolesya @GulayseDunn @HelsinkiUniMed @helsinkiuni @STEMMProgram @ASW_lab @HiLIFE_helsinki
.@ignatenkolesya @GulayseDunn @AWartiovaara et al show that mitochondrial DNA depletion in astrocytes causes abnormal primary #cilia morphology w/ aberrant induction of motile cilia factors bit.ly/3TJcqex From the Year in Cell Biology bit.ly/46vsYNn #Cellbio2023
Tänään @HelsinkiUniMed mitokondriotautipäivä, Biomedicum Helsinki ja zoom. Lauantaina vihreät rakennukset Australiasta Suomeen ja Amerikan mantereelle muistuttavat potilaiden viestistä: toivo on tutkimuksessa. @helsinkiuni
Tule mukaan avoimien ovien MitoPäivään torstaina 21.9. klo 15:00 alkaen Biomedicumissa ja webinaarissa. Lisätietoja: helsinki.fi/fi/tutkimusryh… #WorldMitoWeek #LightUpForMito
Join us for Mitochondrial Disease Open Doors on Thursday 21 Sept at 15:00 (GMT+2) on site or remote! Further details: helsinki.fi/en/researchgro… #WorldMitoWeek #LightUpForMito
#WorldMitoWeek is upon us! Rohit Verma joins us to explore the intricacies of mitochondrial disorders, patients' daily challenges, and treatments to manage these conditions. SoundCloud bit.ly/3EHDQMJ Spotify bit.ly/3ZmdARC ApplePod bit.ly/3Zjl4EZ
Mitä ovat mitokondriotaudit? #WorldMitoWeek avoimien ovien MitoPäivä Biomedicumissa, 21.9. klo 15-18. Tule tutustumaan mitokondriotauteihin ja niiden tutkimukseen, potilaiden ja perheen kertomuksiin, kuulemaan lääkärien ja @neuroliitto asiantuntemusta. helsinki.fi/fi/tutkimusryh…
For the #WorldMitoWeek @ASW_lab @HTyynismaa and @FhrcGracile are organizing an open doors day, with scientists, patients & families, doctors and @neuroliitto patient union talks. 21.9. at 15-18 EET. In Finnish, translated to English in zoom. Follow link: helsinki.fi/en/researchgro…
Being a scientist is the best job. When the lab becomes silent on Friday evenings, the ideas from the past week start to get together and bubble. Alone in the office, content and energized. So happy to work with you all @ASW_lab!
Very excited to follow the entry of the 1-yr-old startup @NADMED_Ltd to USA market via partnering with @TruDiagnostic NADMED is an innovation that was initiated in my @ASW_lab developed by docent @LiliyaEuro prnewswire.com/news-releases/…
Our January cover shows a scanning electron microscopy micrograph of ependymal cells lining the surface of a mouse brain ventricle. From @ignatenkolesya et al @ASW_lab (bit.ly/3hKkL4D). Read JCB’s January Issue: bit.ly/3BXac5c
Mitochondrial dysfunction in CNS manifests with neurodegeneration and reactive gliosis, traditionally explained by vulnerability of [their majesty] neurons. We thought it may not be the full story... and found critical astrocyte contribution to the pathology! 🤓 1/
Mitochondrial dysfunction induces motile ciliogenesis program in astrocytes! 😯 By @ignatenkolesya @GulayseDunn @AWartiovaara from @ASW_lab and colleagues @helsinkiuni @STEMMProgram: bit.ly/3TJcqex #CellMetabolism #Disease #CellSignaling
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