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ACS Central Science

@ACSCentSci

EiC @CarolynBertozzi and ACS Central Science team on #openaccess research at the interfaces of chemistry, biology, materials science, physics, & engineering

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We're delighted to see Editor-in-Chief @CarolynBertozzi recognized, alongside colleagues Sharpless & Meldal, in this way for one of her many considerable achievements! 😍👏🏼🥳🎉 #ChemNobel @NobelPrize

BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”

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A de novo design strategy that leverages directed mutation driven HTVS to evolve vast virtual libraries and screen peptides with ultrahigh affinities for various target proteins NEW #ASAP by Xiaohong Zhou & colleagues at #TsinghuaUniversity Read it here: go.acs.org/bF4

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A Conversation with Raffaele Mezzenga The ETH Zurich materials scientist discusses putting the proteins in food waste to work NEW #CenterStage in collaboration with @cenmag Read it here: go.acs.org/bEd

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Eureka Moments Shared by Chemists. Hints at Enhancing One’s Own Creativity (and Even One’s Joy) NEW #InFocus by Jeffrey Seeman & @JudyWuChem Read it here: go.acs.org/bDk

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Single-Center Trifunctional Organocatalyst Enables Fast and Controlled Polymerization on N-Carboxyanhydride NEW #ASAP by Runhui Liu, Yueming Wu & colleagues at #EastChinaUniversityofScienceandTechnology Read it here: go.acs.org/bCj

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Marinopyrrole A derivative MA-D1 shows anti-MRSA activity by targeting GlmS to inhibit cell wall biosynthesis. This discovery provides a novel target and a lead for developing new antibiotics NEW #ASAP by Xiaoguang Lei, Yong Qin & colleagues Read it here: go.acs.org/bBA

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Inspired by a “theory-first” paradigm, a piperazine-based covalent organic framework (Pip-COF) was designed to capture low-concentration CH3131I under high-flow rate NEW #ASAP by Shuao Wang, Chao Zhao, Long Chen & team at #SoochowUniversity Read it here: go.acs.org/bzI

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Subetadex-α-methyl, a chemically modified polyanionic cyclodextrin, can bind and sequester synthetic opioids as a way to neutralize their toxic effects NEW #ASAP by Carlos Valdez, Michael Malfatti & colleagues @Livermore_Lab Read it here: go.acs.org/byF

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Our NEW issue is now live! Read it here: go.acs.org/bxE Supplementary cover story by Zongbi Bao, Kai Qiao & team #ZhejiangUniversity go.acs.org/bxD

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A configurable nanoconfinement system was built upon pneumatically actuatable microfluidic devices to enable hydromechanical modulation and patterning of surface enzymatic reactions NEW #ASAP by @ZengGroup @UFChemistry Read it here: go.acs.org/bwV

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Start-Ups Are Supercharging Algae to Clean Up the Environment NEW #HUB in collaboration with @cenmag Read it here: go.acs.org/bw1

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Bifunctional Catalysts Synthesized from Hierarchical Materials and Highly Dispersed Metallic Particles: A New Approach NEW #FirstReactions by Juan Cecilia & team discussing work by Jihong Yu & team go.acs.org/bun Read it here: go.acs.org/bum

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Unlocking Terpenoid Transformations: C–H Bond Functionalization for Methyl Group Substitution, Elimination, and Integration NEW #FirstReactions by @laurenammurray discussing work by @HartwigGroup go.acs.org/bts Read it here: go.acs.org/btr

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Our NEW issue is now live! Read it here: go.acs.org/bsq Supplementary cover story by @JianHe_HKU @HKU_Chemistry @hku_science go.acs.org/bsr

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Noncovalent n → π* Interactions in Collagen: The Key for Everlasting Bonds? NEW #FirstReactions by @TheRubiniGroup discussing work by Ronald Raines & team go.acs.org/brF Read it here: go.acs.org/brE

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@ACSCentSci In the News! Explore this ACS press release: "Carbohydrate polymers could be a sweet solution for water purification": go.acs.org/bqA Read the original article: go.acs.org/bqz

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Revealing distinct N-glycan structural signatures of human IgG subclasses by a nano HILIC-LC-MS/MS NEW #ASAP by Weiwei Wang @WANGWEIWEI2022 and Albert Heck @HeckLab Read it here: go.acs.org/bov

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Our NEW issue is now live! Read it here: go.acs.org/bnC Front cover story by @MJCliffe & Joe Paddison go.acs.org/bnB

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#ICYMI Our NEW issue is now live! Read it here: go.acs.org/bmA Supplementary cover story by @EppsGroup @DrLkorley & team go.acs.org/bmz

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.@sarit_agasti’s group @jncasr reports a unique supramolecular strategy leveraging cucurbit[7]uril host-guest recognition to design highly efficient fluorogenic probes for bioorthogonal imaging NEW #ASAP Read it here: go.acs.org/blw

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New Rocaglate Derivatives Tip the Scale against Brain Tumors NEW #FirstReactions by @IwasakiLabRIKEN discussing work by @porco_lab go.acs.org/bkr Read it here: go.acs.org/bkq

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