Toomas Erik Anijärv 🇪🇪
@teanijarvPhD student at @lunduniversity @biofinder_study 🇸🇪 #mri #alzheimersdisease | Adjunct Fellow at the Thompson Institute of @usceduau 🇦🇺 #eeg #ketamine
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@allyneuro
@BraitLab
@_ainiah_
📢The CHMP recommends authorising a new treatment for early #AlzheimersDisease in the EU. Leqembi is intended for treatment of mild dementia and cognitive impairment in a restricted patient population with a specific genetic make-up. 👉 ema.europa.eu/en/news/leqemb…
Cortical maps manifest hemispheric asymmetry in various forms and scales. Our attempt to unveil them through 🧠 eigenmodes: doi.org/10.1101/2024.1… Work led by Alicia Milloz✨
Check out @allyneuro ‘s first paper, part of her PhD on the neurophysiological mechanisms of sustained attention and aging!
🧠 Exciting new findings from our study on brain function and ageing! We explored the relationship between brain oscillations and sustained attention in healthy older adults using resting-state EEG data. Here’s what we found: 🧵👇
Interested in combining neuroimaging and multiomics in AD? Check out our new review on this topic, just published in Cell Reports Medicine. We focus on integration with amyloid- and tau-PET and all the challenges that come with it. w/ @NiklasMattsson4 cell.com/cell-reports-m…
Big thanks to the BioFINDER team for two great days! During our workshop we sharpened our visions for the future, optimized our database structure and learnt from the clinicians how different clinical assessments are done.
🚨Publication in @JAMA_current 🚨 Blood biomarkers to detect Alzheimer’s disease in primary and secondary care, published today in JAMA led by @SebastianPalmqv: jamanetwork.com/journals/jama/…
The figure we all have to learn by heart: The updated Lancet Commission on potentially modifiable risk factors for dementia. #AAIC24
My first paper, entitled “CSF glial biomarkers are associated with cognition in individuals at risk of Alzheimer’s disease”, has been published in Alzheimer’s & Dementia @alzdemjournals! Thread 👇🏽
I am hiring a research technician to help process and analyze multimodal neuroimaging data. Please RT!! * Great opportunity to gain research experience pre-PhD * Access to exciting data * Opportunities for independent projects Apply here: lu.varbi.com/en/what:job/jo…
Super proud to be #Estonian as we are again one step closer to medicine 4.0. Besides different health risks, I also now know I’m 2.51% neanderthal and my ancestry reaches even Asia. nature.com/articles/d4158…
🚨Paper alert Led by PhD student @SEMastenbroek “Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology” now published in @NatureComms ! nature.com/articles/s4146… We found a novel brainstem-first Lewy body subtype 👇
🚨New publication out in @NatureComms led by @karlssonlinda1! We introduce CSF reference proteins: a way to account for the non-disease related signal in CSF protein levels that varies between individuals and affects biomarker performance. doi.org/10.1038/s41467… Detailed 🧵👇
🚨New preprint!! biorxiv.org/content/10.110… Led by PhD student @karlssonlinda1, we reveal a confounding signal in CSF proteomics data and present a new method to address it! Our method results in better biomarkers and, without it, spurious findings can arise. Check out this thread👇
Todays lunch seminar offered many captivating talks! We learned by @teanijarv the impact of asymmetrical #tau aggregation in #AD, by Srisaiyini Kidnapillai about the current advances in glia to #interneurons #reprogramming, and by Filip Fredlund how #MHCII impact #PD pathology.
Wonderful summary by Hanny Le from our team documenting EEG spectral signature similarities and differences amongst the available psychedelics. Helpful guidance for research and mechanistically informed development pubmed.ncbi.nlm.nih.gov/38570038/
‼️ Postdoc ad // Please RT/circulate ‼️ Are you interested in * Big euroimaging and multi-omic data? * Neurodegenerativ disease? The @biofinder_study is looking for a talented postdoc to sink their teeth into some rare and exciting data! Apply here: lu.varbi.com/en/what:job/jo…
❗️Publication❗️ Head-to-head comparison between a highly accurate plasma biomarker and FDA-approved and clinically used CSF biomarkers 🩸#ptau217 is clinically comparable or superior to CSF biomarkers to detect #Alzheimer's pathologies @NatureMedicine nature.com/articles/s4159…
Just finished writing my annual review of my work and adventures during 2023. Long story short, I travelled a lot, moved to Sweden, and started a PhD! toomaserikanijarv.com/blog/2023-star… #PhD #phdvoice #AcademicChatter
‼️New preprint‼️ 🔗Led by PhD student @SEMastenbroek, we unveil three different progression patterns of Lewy body pathology. Disease progression modeling of: * Postmortem Lewy-type α-synuclein data from 10 🧠 regions * N=814 donors 👇👇👇 biorxiv.org/content/10.110…
Are you interested in Alzheimer's disease and other dementias, with specific interest in genetics🧬? Would you like to be part of a team that does cutting-edge research? We have a post-doc (lu.varbi.com/en/what:job/jo…) and a PhD (lu.varbi.com/what:job/jobID…) position available!
Just participated in this 5-day fMRI workshop at @MGHMartinos in Boston, USA - definitely recommend it!
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