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Joshua Ho

@joshuawkho

Associate Professor @hkumed, Lead Scientist @HKU_D24H, bioinformatician, single cell enthusiast, digital health technologist, STEM educator

Joined March 2015
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Joshua Ho Reposted

Self-diagnosis for valvular heart disease made possible? 🩺 And just with our phones? 📱 Check out #SBMS Professor Joshua Ho’s interview where he introduces this award-winning and innovative AI #HKUMed invention, at youtube.com/watch?v=ck8ry2…

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Joshua Ho Reposted

The Hong Kong PhD Fellowship is open for application now! Successful applicants will receive a monthly stipend of >HKD 28K plus >HKD 14K annual conference support. Interested students of high caliber, please contact me for potential nomination gradsch.hku.hk/prospective_st…


Joshua Ho Reposted

Preprint on "BWT construction and search at the terabase scale". We can compress 100 human genomes to 11GB in 21 hours, find SMEMs with it, do affine-gap alignment and retrieve similar local haplotypes. 7.3Tb commonly sequenced bacterial genomes ⇒ 30GB arxiv.org/abs/2409.00613

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Joshua Ho Reposted

Our Co-Principal Investigator Professor Jean Yang & Post-doctoral Fellow Dr Yue Cao from @Sydney_Uni will take part at the “Single Cell Data Analysis Workshop - Unlocking Single Cell Spatial Omics Analyses with SCDNEY” on Sept 9, 2024. linktr.ee/hkucpos_bioinfo @hkumed @hkucpos

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We look forward to welcoming our Australian friends to visit us in HK! I am sure we will learn how AI can be used in digital health with Prof Jinman Kim @hkumed @hkusbms @sydneybioinfo

The @HKU_D24H and @hkusbms will jointly organise a seminar “Multi-modal Learning for Biomedical Image Analysis and Visualisation” on Sept 9, 2024, featuring Professor Jinman Kim from @Sydney_Uni & Co-Principal Investigator of @HKU_D24H Details: d24h.hk/reg/ @hkumed

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Joshua Ho Reposted

The @HKU_D24H and @hkusbms will jointly organise a seminar “Multi-modal Learning for Biomedical Image Analysis and Visualisation” on Sept 9, 2024, featuring Professor Jinman Kim from @Sydney_Uni & Co-Principal Investigator of @HKU_D24H Details: d24h.hk/reg/ @hkumed

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Nice collaboration with @kevin_tsia’s team and @YuanhuaHuang We hope this tool will make a difference in atlas scale cell analysis!

🍾Excited to share our integrated spatial-temporal multiomics tool, 𝐒𝐭𝐚𝐕𝐢𝐚, is finally @GenomeBiology In 𝐒𝐭𝐚𝐕𝐢𝐚, you can: 💡 analyze atlas-scale spatial+temporal omics, single-cell multiomics data in this single tool. 🔎use 𝗔𝘁𝗹𝗮𝘀𝗩𝗶𝗲𝘄 to generate a unified…



Joshua Ho Reposted

XClone is now online @NatureComms after long revisions w/ multiple expansions / changes: CNV>CNA, whole genome duplicate alert, a new allelic CNA simulator, & more! For Scanpy fans, you can stay in py & enjoy XClone as easy as inferCNV :) doi.org/10.1038/s41467…

Excited to share our XClone for detecting allele-specific subclonal copy number variations from scRNA-seq data by integrating both expression depth and phased-allele imbalance. biorxiv.org/content/10.110…



Joshua Ho Reposted

Next Monday, @joshuawkho from @hkumed will present: Scalable analysis methods for single cell and spatial omics data and lineage tracing. ⏱️August 12, 1pm (AEST) 👉bit.ly/3WWjSXx

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Joshua Ho Reposted

Our #QUEST trial results are out in @NatureMedicine! 3,110 patients randomized to #QLQX vs placebo. Primary composite outcome (HF hospitalization + CV death): 25.02% QLQX vs 30.03% placebo (HR 0.78, p<0.001). nature.com/articles/s4159…


Last week we celebrated the graduation of my first group of PhD students and a MBBS/MRes(Med) student since joining @hkumed I am glad to have played a little part in their career.

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Joshua Ho Reposted

Our Lead Scientist @joshuawkho & his team attended the Innovation and Technology Commission’s Reception for I&T Awards 2024 yesterday, where the Hong Kong Chief Executive Mr John Lee congratulated the award winners of various local research and innovations. @HKUMed @vitomeltd

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Joshua Ho Reposted

CellContrast now on @Patterns_CP If only having single-cell but no spatial RNA, you may consider using it to infer spatial adjacency. It helps reduce false positives in detecting communicating cell pairs. We welcome issues and support customized designs. doi.org/10.1016/j.patt…

Excited to share our new preprint CellContrast, a computational method to infer the spatial location for single-cell RNAseq data. Based on contrastive learning, this method is particularly powerful in preserving the local neighbourhood. biorxiv.org/content/10.110…



Joshua Ho Reposted

We're thrilled to announce that iMeta has achieved its first Impact Factor: 23.7! 🎉👏 Huge thanks to our authors, reviewers, editors, and readers for their incredible contributions!

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Joshua Ho Reposted

More info: apbjc.asia #apbjc

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Joshua Ho Reposted

Happy to be part of the HKU team participating in the World Conference on Research Integrity in Athens. Have already learnt much from experts on issues such as paper mills, reproducibility and open science. @WCRIFoundation

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Joshua Ho Reposted

Our system #DigitHeart allows clinicians to take a photo of #ECG using smartphone, automatically have the ECG waveform extracted and converted to voltage-time series, and perform diagnosis classification. #HKUMed heart.bmj.com/content/early/…


Joshua Ho Reposted

We asked three HKUMed scientists how they are using artificial intelligence to aid their research. From detecting cancers to assessing heart attack risk, here’s a snapshot of how AI is being used in medical research: buff.ly/3v6KU4m @joshuawkho @ChuiCeline

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Joshua Ho Reposted

Our workshop on 26/4 introduced participants to basics of R and RStudio. With practical sessions focused on manipulating biological data tables, participants gained valuable hands-on experience. #Bioinformatics #RProgramming #RProgrammingLanguage #DataManipulation #BiologicalData

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