Max Jan
@janlabmghPhysician Scientist | Targeted Protein Degradation | Cell Therapy
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Building our team! Seeking excellent students, postdocs, and scientists interested in contributing to #syntheticbiology, #immunotherapy, #CARTcell at MGH. Please share or reach out for more info! janlabmgh.org/apply massgeneral.org/cancer-center/…
Singularly the best news - the Chemistry @NobelPrize to @CarolynBertozzi !!!! with Sharpless and Meldal Deepest congrats Carolyn, so so well deserved and excited for you.
We recently reported @BCD_AACR that IFNg is not required for CAR-T efficacy in heme malignancies, but what about solid tumors? Out now @Nature, we found that IFNg signaling is crucial for proper engagement and killing of solid tumors by CAR-T. @MarcelaMaus #science #celltherapy
Nature research paper: CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours go.nature.com/3jHTgG9
Delighted to share our work optimizing CAR-T cells for acute myeloid leukemia. We're working rapidly on this devastating disease and will be presenting our dual targeting strategy building on this publication in May @ASGCT in Washington DC @Cancer_Cell cell.com/cancer-cell/fu…
The first datasets from our degradation proteomics initiative were sent out over the last few weeks!! 🎉 If you’re interested in free global proteomics screening of degraders for target ID and mapping please get in touch and I can provide further details.
🥳new pre-print!🥂 Clonal mosaicism is THE frontier in human genetics. But we know next to nothing about phenotypes of mutated cells in humans. Single-cell multi-omics allowed us to link genotype-phenotype directly in primary human clonal hematopoiesis🎉 biorxiv.org/content/10.110…
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Who to follow
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bryan dickinson
@chembioBryan -
Cigall Kadoch
@CKadoch -
Evan Weber
@EvanWeberPhD -
Georg Winter
@georg_e_winter -
Fischer Lab
@fischerlab1 -
Brian Liau
@brian_b_liau -
Stegmaier Lab
@KStegmaier_DFCI -
Dan Nomura
@DanNomura -
Ryan Flynn
@raflynn5 -
Milka Kostić, PhD
@MilkaKostic -
Alexander Hanzl
@AlexanderHanzl -
Hojong Yoon
@hojong_yoon -
Namita
@Nambit_Saria -
Jana Ellegast
@JanaMEllegastMD -
Adam Sperling
@adamssperling
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