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Karmel S. Gkika

@gkika_s

BRI-FORTH

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Karmel S. Gkika Reposted

New study in human brain organoids, led by @KleanthiChalki1 on the CNTNAP2 autism risk gene role in early cortical development. We see GABA/Glutamate neuron differentiation imbalance & hyperactive Akt/mTOR. @johnomason @BRI_FORTH @FORTH_ITE @ELIDEK_HFRI bpsgos.org/article/S2667-…

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Karmel S. Gkika Reposted

Another great Chemistry Day organised by @PGAC_DCU! ✨ It was lovely to see the research going on in the school & I'm delighted to have won the Colin Barnes Award 🧑‍🔬🧬

Huge congratulations to all of our award winners for their brilliant presentations at Chemistry Day!🏆 Your contributions were truly impressive and inspiring. Keep up the great work! #ChemistryDay #DCUChemistry @DCUChemistry

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Karmel S. Gkika Reposted

New Frei Lab Preprint is Online, go check it out!

Our latest Preprint is live @ChemRxiv: doi.org/10.26434/chemr…! Here we report the further exploration of Rhenium Bisquinoline Complexes as Antibacterial Agents with first Mode of Action studies (1/8)

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Karmel S. Gkika Reposted

Professor Tia Keyes @DCUChemistry has been awarded the prestigious Boyle-Higgins Gold Medal and Lecture Award from @irishchemistry - Prof Keyes will deliver a lecture at the Awards Ceremony on 18th April at UCD O'Brien Centre @DCU @DCU_Research chemistryireland.org/latest-news/

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Karmel S. Gkika Reposted

Mazen is a 2nd year PhD in my team, focusing on developing responsive #probes for #fluorescence quantification of #ROS and correlation of #ROS level with macrophage polarisation. Mazen's 1st paper of .OH probe published on @ChemAsianJ onlinelibrary.wiley.com/doi/10.1002/as…


Karmel S. Gkika Reposted

We use them every day, but have you ever wondered how computer chips are made? One of the key steps has close ties to a 19th century invention - check out my article for @RTEBrainstorm for more info. @DCUPhysics @DCUResearchNano

How a 19th century invention helps produce powerful computer chips. By Stephen Durkan @DCUPhysics @DCUResearchNano @DCU @scienceirel rte.ie/brainstorm/202…



Karmel S. Gkika Reposted

#manganese #photochemistry: Oxidative two-state photoreactivity of a manganese(IV) complex using near-infrared light – it’s a very powerful luminescent photooxidant. rdcu.be/dx9iy Now published in nature.com/articles/s4155… @LabHeinze @uni_mainz_eng


Karmel S. Gkika Reposted

Vascularize Neural #Concentroid (fusion of ~130 PSC-derived neuroprogenitor spheroids) using iETV2-#EndothelialCell Elaborating a neurovascular network in Matrigel🥸 Transplant this vascularized neural #Organoid into🧠? #AdvSci 2023 @AdvSciNews onlinelibrary.wiley.com/doi/10.1002/ad…

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Karmel S. Gkika Reposted

Calling early career acientists for the first ever Metals in Medicine GRS! Treat yourself this holiday season and submit an abstract ❤️ @SophieT99879381 rb.gy/vaw7ur #metalsinmedicine

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Karmel S. Gkika Reposted

Great collaboration with our Polish colleagues: Major review on siderophores is out now, actually the first on coordination chemistry aspects of arylthiazoline and aryloxazoline siderophores. Thanks to everyone @BioInorgChemWro @WCh_UWr @ruhrunibochum authors.elsevier.com/sd/article/S00…

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Karmel S. Gkika Reposted

Excited to share our results that the RNA base acp3U is an attachment site for N-glycans in glycoRNA by coupling native glycoRNA labeling (rPAL) w/SWATH-MS Led: @axe_xie @HelenaHemberger Critical collab @GarciaLabMS @CarolynBertozzi, @BCHStemCell @HSCRB biorxiv.org/cgi/content/sh…

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Karmel S. Gkika Reposted

New Tridentate Ligand Affords a Long-Lived 3MLCT E. S. in a Ru(II) Complex: DNA Photocleavage and 1O2 Production pubs.acs.org/doi/10.1021/ac… Thummel, Turro, & co-workers @InorgChem #ruthenium #dppz #quinolinl #tpy #180deg #1O2 #visible #3MLCT #3LF #DNA #intercalation #cleavage

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Just like Autumn, I am embracing change. Excited for my new postdoctoral role! @RCSI_Micro @RCSI_Irl 🔬🧫

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Karmel S. Gkika Reposted

Responsive probes for #luminescence detection & #imaging of #DNAzyme, reviewed by Prof C.-Y. Zhang and F. Ma at Southeast University, published in TrAC @ELSchemistry Thank the authors and anonymous reviewers for their great support sciencedirect.com/science/articl…


Karmel S. Gkika Reposted

Very glad to see the 2 works published! #ultrafast #dynamics

Delighted to share our most recent publications: "Excited-State Dynamics following Photolysis of Cu(II)-Porphyrins" and "Incorporation of perylene and naphthalene like ligands into ruthenium complexes". ☺️ @MaREIcentre @scienceirel @Ross_J_McGarry @MartynaBartusi1 @AresLazaros



Karmel S. Gkika Reposted

On-Resin Conjugation of the Ruthenium Anticancer Agent Plecstatin-1 to Peptide Vectors | Inorganic Chemistry pubs.acs.org/doi/10.1021/ac… @HartingerHub and co-workers @InorgChem #ruthenium #piano_stool #plecstatin1 #TAT48_60 #neurotensin8_13 #plectin_targeting_peptide #anticancer

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Karmel S. Gkika Reposted

Super excited about this! Check out manuscript from my amazing postdoc Eric Mulhall and collaborators measuring single molecule #PIEZO1 dimensions in cells with nanometer precision using super-resolution fluorescence microscopy: nature.com/articles/s4158… 1/9


Karmel S. Gkika Reposted

This is the story of Georgios Papanikolaou and his wife Andromachi (Mary) Mavrogeni Papanikolaou. Born on the Greek island of Euboea in 1883, Georgios received a medical degree in 1904 from the National University of Athens. Upon graduation, he worked in the military as an…

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