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@TheWebbLab
@gio_SiGa
@NathanShockCtrs
@arpit_science
@SCAgingBrain
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@Yufei_Lin26
@KPapsdorf
@MarySalib8
@woodboy
Thrilled to share our paper online @Nature (on my birthday)! We've identified a new population of LepR neurons (BNC2) in the hypothalamus ARC that acutely suppresses appetite by directly inhibiting AGRP neurons, decoding the missing LepR GABAergic neurons. nature.com/articles/s4158…
Can we use CRISPR screens to identify genes that drive neural stem cell aging? Super excited to see this work published @Nature! Huge congrats to Tyson @ruetz_tyson, Angie Pogson, @kashiwagi_chloe, and all authors! Great collaboration with @MCBassik! nature.com/articles/s4158…
What causes Alzheimer’s disease? Scientists are searching for the answer. It’s likely a combination of brain changes, genes, and factors related to health, the environment, and lifestyle. Learn more: go.nia.nih.gov/3WIVrhB #NIAAlzheimers
🎉 Thrilled to share our latest method, IRIS, now published in @naturemethods！IRIS is a robust statistical and computational method designed to decode the spatial organization of tissues. It efficiently detects biologically interpretable spatial domains across multi-samples.
Integrative and reference-informed tissue segmentation (IRIS) from Ying Ma & Xiang Zhou harnesses scRNA-seq data for the accurate identification of spatial domains in spatially resolved transcriptomics. IRIS is uniquely suited for analyzing large datasets. nature.com/articles/s4159…
Beyond thrilled to share 3 papers on the killifish from our lab and fantastic collaborators!! 🐟🙌 Two on protein aggregates during aging – with @JaroszLab! cell.com/developmental-… cell.com/cell-reports/f… One on evolution of 'suspended animation'! cell.com/cell/fulltext/…
Excited to announce the inaugural AIMBA (AI Meets Biology of Aging) 2024 meeting on May 22, 2023, 9-2pm PT, organized by @UW @NathanShockCtrs ! Featuring four keynote speakers: Profs @mariabrbic, Anne Brunet, Vadim Gladyshev, @james_y_zou Check it out! sites.google.com/cs.washington.…
So proud of @AngelinaHolcom for winning a poster prize for her work on metabolic regulation of neurogenesis at the Bay Area Aging Meeting! 😎 @BuckInstitute
Incredibly excited to share our paper on the impact of partial reprogramming on neurogenic niches of the old brain (in mice)!! Massive congratulations to first-author Lucy Xu and all the authors!! 🌟🙌🍾 nature.com/articles/s4358…
Congratulations to Buck students @kels_babcock and @FrancescoNeri_ for their award-winning poster presentations at #BAAM2023! 👏👏👏
Thrilled to see our latest work out in @CellReports! Spearheaded by @doudou_yu_ and in collaboration with ML expert Ritambhara Singh (Brown U). We developed a new ML pipeline to classify cellular age in scRNA-seq datasets from the brain. @BuckInstitute cell.com/cell-reports/f…
CellBiAge: Improved single-cell age classification using data binarization dlvr.it/SzX2C3
We are recruiting 1-2 postdocs to work on mechanisms of brain aging and neurodegeneration! ✨Join us @BuckInstitute ✨
So excited to see my review with @TheWebbLab and the Fallon lab is the most read paper from @stemcellreports !! 🤯🤩 I’m very proud of our work in understanding #neurogenesis in #aging and #Alzheimers 🧠
Adult hippocampal neurogenesis in aging and Alzheimer's disease @kels_babcock @TheWebbLab @BrownUNeuro Most read paper from @stemcellreports @ISSCR @martinperaJAX hubs.ly/Q01K5wVJ0
May the force be with us today! Our First ML/AI manuscript on predicting neuronal age from single cell RNA-seq datasets is submitted! Congrats @doudou_yu_ @BrownCCMB @KHajdarovic Also, in case you're interested...average lifespan of a wookiee: 400 years!!!
Can we build 'aging clocks' in different cell types to measure the impact of aging and 'rejuvenation'? ⏲️ Massive congrats to @MatttBuckley and @EricDSun!🍾🎉🙌 rdcu.be/c1TPK @NatureAging Great collaboration with #IrvWeissman @wysscoray @Goodell_Lab @Thomas_Rando!
Check our our latest review on the aging hypothalamus! We discuss recent advances made possible by the use of single cell 'omics approaches and highlight outstanding questions in the field. Well done @KHajdarovic @doudou_yu_! @BrownBoA @CarneyInstitute cell.com/trends/neurosc…
'Understanding the aging hypothalamus, one cell at a time' Kaitlyn Hajdarovic @KHajdarovic, Doudou Yu @Doudou_Yu_ & Ashley E. Webb @TheWebbLab cell.com/trends/neurosc…
Understanding the aging hypothalamus, one cell at a time @KHajdarovic, @doudou_yu_ & @TheWebbLab sciencedirect.com/science/articl… @TrendsNeuro
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Who to follow
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Webb Lab @ The Buck Institute
@TheWebbLab -
Gio Silva-García
@gio_SiGa -
Nathan Shock Centers
@NathanShockCtrs -
Arpit Sharma, PhD
@arpit_science -
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@SCAgingBrain -
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@YAlvinHuang -
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@MikeMacArthur8 -
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@Yufei_Lin26 -
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@KPapsdorf -
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@MarySalib8 -
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@woodboy
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