Mezida Saeed
@docmezid#habesha interested in immune cell biology - PhD Immunology & BSc Pharm/Phys @fbmh_uom 🇬🇧 - she/her
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@nizzle_fe_shizz
@AkbarLab
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@JonathanWorboys
@grencisgroup
@TravislabUoM
@sarahdezperez
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@HussellTracy
Cytokines remodel the ribosome to incorporate the P-stalk, therefore altering the translation of mRNAs involved in cytokine responses @CellCellPress cell.com/cell/fulltext/…
Please SHARE: Deadline approaching for applying to postdoc positions studying synaptic homeostasis via single-molecule methods @dandrite @NordicEMBL @MolBiolAU
My lab is looking for 1-2 postdocs funded by @lundbeckfonden and DNRF center fund to study molecular homeostasis at synapses at @dandrite @AarhusUni_int @MolBiolAU ! nature.com/naturecareers/…
#Postdoc Opportunity: Interested in learning how cells translate mechanical stimuli into changes in gene expression? Join our nuclear #mechanotransduction team at @CornellBME and @weillinstitute Strong background in #bioinformatics desired. tinyurl.com/mechanobiology… Please RT!
Happy to see our story on tolerance to inflammation antigens @NatImmunol nature.com/articles/s4159… It grew from a naive question I had at my first immunology class: if some self molecules are only induced by pathogen how does immune system distinguish them from foreign antigens?1/n
Special issue on "The cancer-immunity cycle," a concept first introduced by Mellman & Chen in 2013 that provided a framework to understand anti-cancer immunity | Seven articles discussing progress & advances in the field & highlighting key challenges #cancerimmunitycycle…
We studied the how much’s and the where’s of a key self-tolenergic molecule using #volumetric, #superres microscopy. A wonderful collaboration with @ThuyLuu,@PetterHoglund et al now in shiny print.
Researchers find that the spatial distribution of #SHP1 within mouse #NaturalKillerCells shifts during NK cell education by being sequestered away from activating immune synapses, hinting this mechanism may facilitate self-tolerance. @karolinskainst scim.ag/2eF
Impactful findings on how the mechanobiology of the nucleus affects levels of alveolar macrophages and associated vulnerability to their loss in aging and resp infection. Elegent mouse mechanistic insights with huge potential for translational insight👌🏾
And there was more very interesting work presented today 🔥😏 @docmezid from @karolinskainst presented a #preprint by @NicolasManelLab showing how nuclear rupture in alveolar macrophages triggers cellular ageing 👴👇 biorxiv.org/content/10.110…
Here's our latest paper for fans of super-resolution microscopy and/or lung macrophages. Led by @ash_ambrose and Susanne Dechantsreiter. #microscopy cell.com/biophysj/fullt…
Only a few days left to enjoy our book chapter for FREE: authors.elsevier.com/b/1bv6D6uaSNDm… We explore the regulation of #actin #cytoskeleton in immune cell biology in the context of actin related #PrimaryImmunodeficiencies.
We had a great time putting together this chapter on the different layers of actin filament regulation and the invaluable insights that inborn errors in these regulators provide on various aspects of immune cell biology. sciencedirect.com/science/articl…
This is a seriosuly wonderful conversation! #keepitfun
Here's my interview about the immune system and microscopes bit.ly/microscopists-…
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Looking for a weekend read? Look no further! Higher Incidence of B Cell Malignancies in Primary Immunodeficiencies: A Combination of Intrinsic Genomic Instability and Exocytosis Defects at the Immunological Synapse frontiersin.org/article/10.338…
🚨 20 million euros to unlock secrets of cell division and test ‘liquid crystal’ hypothesis CRG’s Vivek Malhotra & Thomas Surrey are part of two international consortia awarded with an ERC Synergy Grant #ERCSyG to pursue 2 radical ideas in cell biology ➡️bit.ly/2U95riR
Bleak 🌧 morning brightened up hearing @Agingfencer describe how the immune systems pursuit of lagom (just right) makes #tumorimmunology wonderfully complicated.
New paper out! Meet the new dye Pro12A! In collab. with @aklymchenko @Lab_Klymchenko , we redesigned Laurdan probe to make it plasma membrane specific and more sensitive to membrane order! Don't take my word, see Tweetorial for the data. @an_chem pubs.acs.org/doi/10.1021/ac…
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Who to follow
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Christian Franke
@nizzle_fe_shizz -
Akbar Lab
@AkbarLab -
Kathryn Else
@kathelse -
Alex Carisey
@alexcarisey -
werner muller
@wmuee -
Dr Jo Pennock
@immunoJo -
Malcolm Sim
@mjwsim -
Inés
@Ines_DdO -
Felipe Melo González
@felipe_melo -
Jonathan Worboys
@JonathanWorboys -
Grencisgroup
@grencisgroup -
Travis Lab
@TravislabUoM -
Sara Hernández Pérez
@sarahdezperez -
StaggLab
@StaggLab -
Tracy Hussell
@HussellTracy
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