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Birth of a neuron. Stem cell transforming into a brain cell
What did we discover? Along the proximal axon, clathrin-coated pits form at the center of unique circular “clearings” of the periodic actin-spectrin scaffold that expose the plasma membrane 🎯
Introducing The AI Scientist: The world’s first AI system for automating scientific research and open-ended discovery! sakana.ai/ai-scientist/ From ideation, writing code, running experiments and summarizing results, to writing entire papers and conducting peer-review, The AI…
Cells located in the midline of the embryo play crucial roles in development. These cells often influence cell fate decisions and guide axons to establish bilateral connections. Despite their importance, studying these transient cells and their complex interactions has been…
🚀 Excited to share the first preprint from my postdoc in the labs of @ClopathLab and Troy Margrie at @SWC_Neuro! We've reconstructed movies from mouse visual cortex activity. 📽️✨ #Neuroscience #AI 1/6 doi.org/10.1101/2024.0… youtu.be/TA6Oi5NfuMs
Concentric circles made up of tilted arcs appear to be spirals.
Introducing Evolutionary Model Merge: A new approach bringing us closer to automating foundation model development. We use evolution to find great ways of combining open-source models, building new powerful foundation models with user-specified abilities! sakana.ai/evolutionary-m…
Introducing FunSearch in @Nature: a method using large language models to search for new solutions in mathematics & computer science. 🔍 It pairs the creativity of an LLM with an automated evaluator to guard against hallucinations and incorrect ideas. 🧵 dpmd.ai/x-funsearch
Revolutionary 'Anthrobots' show promise in healing & regeneration. These tiny biobots, made from human cells, could pave the way for personalized medical treatments, marking a leap in regenerative medicine and Biotechnology. neurosciencenews.com/anthrobots-cel… Image Credit: Gizem…
We present MEDITRON, a set of new open-access #LLMs (70B & 7B) adapted to the medical domain, achieving new SoTA open-source performance on common medical benchmarks, outperforming #GPT-3.5 and Med-PaLM, and coming within 5% of #GPT4 Find out how we did this ⬇️
Whole brain(!) in vivo gene editing to correct a point mutation in a ASD mice model. Li, Zhang, et al. Nat Neuro nature.com/articles/s4159…
You can hear the words «Green Needle» or «Brainstorm» only based on which one you think about. This is an auditory illusion, or a false perception of a real sound [explanation: buff.ly/3ItCQfg]
Commissural axons growing to and crossing the ventral midline of the 🐥 spinal cord🧐 #FluorescenceFriday #axonguidance #neuroscience
Vesicular transport in a bundle of neurons. Made this movie some years ago. Incredible how much material is constantly being moved around in our cells over long distances by tiny (nanometer scale) motor proteins #microscopy, #science, #cells_are_amazing
We’ve always wondered if there was something beyond CRISPR for genome editing. We now report that animals, plants, fungi and viruses have troves of programmable nucleases capable of efficient gene editing in human cells An update on our Fanzor work! science.org/doi/10.1126/sc… 1/7
Mosaic organoids + Multi-protein labeling + Longest-term organoid LSM + Morphometric demultiplexing + SCG + Biological insight into self-organization of loosely constrained human developmental systems 😍 Super! @Jain_Akanksha_ @GillesGut @TreutleinLab biorxiv.org/content/10.110…
Motor cortex is key for skilled movement, yet how this area develops is still unclear. In a new preprint, we identify developmental genetic determinants of descending motor pathways, and reprogram area-specific connectivity using neuron type-specific TFs. biorxiv.org/content/10.110…
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Who to follow
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AndyXAndersen
@AndyXAndersen -
json
@JsonBasedman -
Kabir Kumar AI-plans.com, (find me on bluesky)
@KKumar_ai_plans -
rohit
@knowrohit07 -
Hausdorff Center
@HCM_Bonn -
losslandscape
@losslandscape -
Kass Popper - e/acc
@foomagemindset -
Sarx
@bookofflesh -
Jason
@mytechceoo -
Sigma Vance
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Sev
@Sevrelu -
Unit Accord
@unit_accord -
Nell0tofo
@nello954 -
EMPRESS ✝️
@empress_net7 -
Akshobya
@albustime
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