Buse Isbilir
@buse_isbilirstructural biology enthusiast | surface layers on bacteria | cryo-EM | conjugative transposons
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Architectural dissection of adhesive bacterial cell surface appendages from a ‘molecular machines’ viewpoint. Underlying common arrangement in adhesins by @_OliviaSmith__ out in @JBacteriology journals.asm.org/doi/10.1128/jb…
I used to be proud to be a part of @The_MRC, but @UKRI_News feels different. The @UKRI_CEO's latest pay settlement where former employees of @The_MRC get 3.7%, whereas the rest of UKRI gets 5.5% is not helping. 😠 Open letter by @ucu and @ProspectUnion: openletter.earth/protest-at-mrc…
We are looking for a post-doc interested in performing structural studies inside tissues. Please apply below or get in touch directly. Access to state-of-the-art equipment and unique expertise in house. nature.com/naturecareers/…
Structure of the virulence-associated Neisseria meningitidis filamentous bacteriophage MDAphi Congrats @janboeh @AbulTarafder @miles_a_graham @MathieuCoureuil @MRC_LMB @NeckerInem biorxiv.org/cgi/content/sh…
Mapping the ultrastructural topology of the corynebacterial cell surface by @buse_isbilir Amazing collaboration with Anna Yeates and @Vikram_Alva @MRC_LMB biorxiv.org/content/10.110…
I am excited to share our new preprint on the structure of S-layers. The work is a collaboration between @OxfordChemistry (Ed Johnston and myself) and @buse_isbilir and @TBharat_lab at @MRC_LMB and @Vikram_Alva at @MPI_Bio 🧵 1/11 biorxiv.org/content/10.110…
Cell cycle dependent coordination of surface layer biogenesis in Caulobacter crescentus. Finally in peer reviewed form with even more data. Congrats @matt_herdman @buse_isbilir and team! rdcu.be/dE8nW
🚨 Position Alert (Please RT) Searching for our next fantastic team member! We have an opening for a #Bioinformatician to join our team @LeibnizFLI! Passionate about CompBio? Experienced or keen on learning diverse data analyses? Learn more & apply: donertas-group.github.io/joinus/
Now published: our study showing how liquid crystals of filamentous phages (termed tactoids) form diffusion barriers, protecting Pseudomonas aeruginosa from antibiotics in biofilms. (1/2) rdcu.be/dtYPO
Glad to share our latest edition of the Caulobacter S-layer story - ‘Cell Cycle Dependent Orchestration of Surface Layer Biogenesis in Caulobacter crescentus’ Congrats @matt_herdman @MRC_LMB @Dunn_School @UniofOxford biorxiv.org/content/10.110…
Delivery of therapeutic molecules is a major bottleneck for treating a wide range of diseases. Today we describe a new modality for delivering proteins based on an engineered contractile injection system @nature nature.com/articles/s4158…
We are #hiring ! We have open #PhD and #Postdoc positions. Both fully ERC funded to work on #transposons and #antibioticresistance spreading. Come and join us at the amazing University of Geneva. If you are interested, contact us directly by email. #UNIGE #CryoEM #MoCel
First full views of a CRISPR-guided system for gene insertion nature.com/articles/d4158…
Asgard archaea reignited discussions about the tree of life 🦠 But do they have eukaryotic features? YES!! 🤩 Check out our new paper @Nature by @F_Wollweber and @xujw_thu, in an exciting collaboration with the Schleper lab @Archaea_Vienna nature.com/articles/s4158… 🧵1/4
Our analysis of translation states in Dictyostelium is now online rdcu.be/c0RCb Subtomogram averaging from FIB lamellae at decent resolution by @pc_hoffmann @jpkreysing @iskhusainov @sonjawelsch and Maarten Tuijtel. #CryoEM #TeamTomo @MPIbp
Two hours until the start of #LHCRun3 🎉💥
The #AlphaFold source code has been updated and now accounts for multi-chain protein complexes - providing a significant improvement in accuracy for predicting protein interactions: dpmd.ai/af-multimer-os Generate predictions from your browser via: dpmd.ai/alphafold-colab
Last year we presented #AlphaFold v2 which predicts 3D structures of proteins down to atomic accuracy. Today we’re proud to share the methods in @Nature w/open source code. Excited to see the research this enables. More very soon! bit.ly/alphafoldmetho… bit.ly/alphafoldgithub
There should be a holiday (once a year) where everybody takes all the papers that they meant to read (but never will) and burn them together (there’ll be food, singing and costumes too)
Our work on tyrosine recombinases in bacteria is now online @MolSystBiol! We predict when these proteins move #transposons just by looking at their sequences. With @Alexbateman1 and @BarabasGroup embopress.org/doi/full/10.15…
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