@ToumyGG Profile picture

Toumy Guettouche

@ToumyGG

Omics enthusiast. Opinions are my own. 🇩🇪⚽️⚪️🔴🐊

Joined October 2012
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Toumy Guettouche Reposted

How well do vaccines protect vs #LongCovid, a systematic review during the Omicron era? —about 20% reduced by primary series (vs no vaccination), and —another 20% reduction by boosters vs primary series medrxiv.org/content/10.110…

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More problems in the DTC genetic testing world.

DNA testing company vanishes along with its customers' genetic data | Malwarebytesl Atlas Biomed malwarebytes.com/blog/news/2024…



I wonder how many academics and life science companies have started contemplating how the next four years might unfold, for example in terms of NIH funding.


Toumy Guettouche Reposted

RFK Jr calls for “8 year pause” on NIH infectious disease research, diverting to chronic diseases Despite significant evidence of infections as candidates for chronic illness cause nature.com/articles/s4158…


Seq-Scope: this protocol enables on-flowcell spatial transcriptomics on an Illumina sequencer, joining Element and Singular on-flowcell methods, though all three methods have somewhat different use cases. Great work @jsantoyo

Seq-Scope: repurposing Illumina sequencing flow cells for high-resolution spatial transcriptomics. @illumina #FlowCell #SpatialTranscriptomics @NatureProtocols nature.com/articles/s4159…



Great work and an awesome thread.

EXCITED to unroll this 🧵 on our new story on the metabolic licensing of animal development... How did we even get here..? shorturl.at/vuCIh Early embryo is thought of a pre-set machine that's set to go once it's fertilized - check out this gorgeous 📽️from Phil Keller!



Wow, Biorad postpones launch of their QX Continuum indefinitely. They also had put their single cell platform on hold. R&D spent doubled. Their recent acquisitions don‘t seem to work out, other than maybe IP. More acquisitions on the horizon? tinyurl.com/mfzcz2du


Alzheimers researchers accused of credible fraud. They have burned millions in funding, earned a lot of money and set back Alzheimer’s research years to decades. None of them are banned from doing Science.

List of high-level Alzheimer's researchers accused of credible fraud:🧵 #1 - Marc Tessier-Lavigne Genentech pointed out problems in his 2009 Nature paper in 2012. After an expose by @tab_delete, he had to resign from Stanford Presidency, but can still run lab and do research.

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If Elmo really gets rid of blocking, I am out. I block multiple accounts each week, most of them clearly bots. On the positive side it will just speed up the demise of this platform.


This is utterly insane. To support a fraud with delusions of grandeur to continue his unethical and flawed research and human experimentation. I hope somehow that this is going to be stopped.

.@MeganMolteni's bone-chilling read about a delusional dilettante whose gene editing "skills" would fail him out of Bio1a - now bernie-madoff-ing some "accelerationists" to support his rampage. = the vile leading the blind. statnews.com/2024/10/08/cri…



Amazing work by @LGMartelotto and the team that developed this technology. It should make spatial multimodal project much more scalable. Cost per cell is two orders of magnitude lower than sequencing based methods.

STAMP: Single-Cell Transcriptomics Analysis and Multimodal Profiling through Imaging | bioRxiv ⁦@DrJasPlummer⁩ ⁦@hoheyn⁩ ⁦@pascual_reguant⁩ ⁦@eliseinsing⁩ ⁦@cnag_eu⁩ ⁦@ACEpigenetics⁩ ⁦@StJudeResearchbiorxiv.org/content/10.110…



Wow, pretty amazing if this works. Though 100kD is very large, it’s a good start, especially if PTMs are included.

Nanopore proteomics is beginning to break wide open. A mass spec on every bench, and as easy and ubiquitous as gels and blots.

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Tardigrades, amazing creatures….

I've seen claims online that tardigrades can live for 30 years without food or water. A Nat Geo article says this, without attribution. My initial reaction was that this must be an estimate. Why would anyone wait 30 years to figure this out? But Japanese scientists actually did.…

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This platform is increasingly (and seemingly with increased velocity) becoming an echo chamber of the sort of people Elmo, Farage and a former US president call their base of supporters.

X/Twitter user numbers now down by almost a third over the last year in the UK, and by almost a fifth in the US.

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Catch 22 vibes

Strong evidence showing that getting a PhD is extremely bad for your mental health. A new paper uses Swedish medical records and matches them to the full population of PhD students for which the authors could get gender and birth year data from 2006 to 2017. After some exclusion…

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And here I thought Eurofins makes oligos when in reality they compete with Consumer Reports….they make Danaher look like a niche market business. businesswire.com/news/home/2024…


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