@Tabdanov Profile picture

Erdem Tabdanov

@Tabdanov

Assistant Professor, Department of Pharmacology, Penn State College of Medicine. Researcher in #cancer and #immunity #biophysics.

Joined May 2011
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Honored and humbled with the fact our works were featured three times by various journals since 2021. 1. pubs.acs.org/doi/10.1021/ac…… 2. onlinelibrary.wiley.com/doi/abs/10.100…… 3. science.org/doi/10.1126/sc…

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The ability of cells to sense and communicate their shape is central to many of their functions. Much is known about how cells generate complex sha... Source: PNAS search.app/cr1XZ4JWCBPoEP…


Not a single speaker from the U.S., hmmm…..

Join us next week in London for the conference « Mechanobiology Shaping Life » organized at the Institute of Physics iop.eventsair.com/msl2025/ 👇🏼

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Erdem Tabdanov Reposted

Is basic science undervalued? David Glanzman talks about the decline of 'middle class' labs and that "there is no empirical evidence that the translational approach accomplishes [cures] any better than the traditional one. Claims to the contrary at this point are mere propaganda”

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Erdem Tabdanov Reposted

How to write a grant? 1. Write it for the reviewer, not you, the applicant. 2. Communicate in stories. 3. Make your story cohesive—leave no puzzling gaps. 4. Make your story resonate to keep the reviewer reading. 5. Accept chance and noise in peer-review. pnas.org/doi/epub/10.10…

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Erdem Tabdanov Reposted

Considering that each group of RVs takes about 0.5s to reach the ground from the cloud, which is about 2 km from the earth's surface, the RVs reach the ground at a speed of about 4 km/s or almost Mach 12. This is breathtaking & staggering! There is no defense against it! 1/4


Erdem Tabdanov Reposted

I’m thrilled that our Spateo work (github.com/aristoteleo/sp…) has been accepted by Cell  (cell.com/cell/fulltext/…) and excited to share it, particularly for the 3D reconstruction, with a broader audience!

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Erdem Tabdanov Reposted

How engineered T cells are changing the face of autoimmune diseases via B cell depletion science.org/content/articl… @ScienceMagazine @NewsfromScience @jcouzin open-access

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We've already seen remarkable results for lupus and other autoimmune diseases with CD19 B cell depletion therapy. Now add IgG4 related disease (which has no treatment) in a new randomized trial @NEJM nejm.org/doi/full/10.10…

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Erdem Tabdanov Reposted
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Lol

First born children have higher IQ than their siblings. 🧵1/9

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Erdem Tabdanov Reposted

We make it to the cover @NatureBiotech! the IL-10-CAR-T cells eradicate solid tumors! nature.com/articles/s4158… The IL-10-CD19-CAR-T cells have shown promising clinical results in several investigator initiated trials too. Stay tuned! #SOHC @myESMO @ASH_hematology

The November issue is live nature.com/nbt/volumes/42… On our cover, Zhao et al. show that expressing IL-10 in CAR T cells improves their mitochondrial function and therapeutic efficacy in multiple solid-tumor models go.nature.com/3vh5Bdv

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Erdem Tabdanov Reposted

"A new perspective on tumor progression" dro.deakin.edu.au/articles/journ…

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Erdem Tabdanov Reposted

We live in incredible times.

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Erdem Tabdanov Reposted

Non-neural human cells can store memories - similar to brain cells. 🧵1/9

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Research Cluster of Bauman Moscow State Technical University by Sergey Kuznetsov in cooperation with TPO “Pride” bureau team amazingarchitecture.com/university/res…


Happy Veterans Day!

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Erdem Tabdanov Reposted

Lee, M., Jeong, H., Lee, C., ..., Shin, J. H., & Park, Y. (2024). High-resolution assessment of multidimensional cellular mechanics using label-free refractive-index traction force microscopy. Communications biology, 7(1), 115. #EpithelialMechanics nature.com/articles/s4200…

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Human breast #cancer cell, i.e., #adenocarcinoma cell (MDA-MB-231), loses structural integrity and generates migratory cytoplasts. The micro-cytoplasts migrate using #dynein-generated forces in the #microtubule network, and are independent of #myosin contractility.

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Erdem Tabdanov Reposted

A geometric #MachineLearning model predicts the collective dynamics of multicellular systems — including cell migration speeds — using only single, static snapshots of their positions, trained and validated on experimental and synthetic data. 🔗 go.aps.org/3Ametlj

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