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ADHD is highly prevalent among adults, affecting 6.0% of the adult population. Despite the widespread prevalence of #ADHD in adulthood, many patients face challenges in accessing care. Read More nei.global/20992
Medical disorders to rule-out before diagnosing #ADHD: Sleep apnea, diabetes, thyroid disorder, absence seizures, concussion, inflammatory bowel disease, iron deficiency, and anemia From review: pubmed.ncbi.nlm.nih.gov/38002482
#Lithium linked to same risk of medical problems as valproate/lamotrigine in supersized, 10-yr observational study, except low thyroid: pubmed.ncbi.nlm.nih.gov/38663126 Follows other studies that challenge assumptions about lithium and renal health. #bipolar #depression #psychiatry
#Antipsychotics keep failing in delirium, again here in randomized trial of haloperidol/ziprasidone: pubmed.ncbi.nlm.nih.gov/38701817 No benefit in "cognitive, functional, psychological, quality-of-life... should not be used routinely to treat delirium" #psychiatry #neurology #medicine
#ICYMI: Dr. Nora Volkow’s recent blog highlights how syringe services for people who inject drugs are enormously effective, but remain underused. Read more of her insights on how syringe service programs can help prevent #HIV: go.nih.gov/wuY6PHN #SSP (2/5)
Temperatures are to go below freezing tonight. If you see anyone at risk, especially those living on the street, please call 311. During #CodeBlue, shelter is available system-wide for anyone brought to a shelter by outreach teams. Accommodations are also available for walk-ins.
Original Article: Twice-Yearly Lenacapavir for HIV Prevention in Men and Gender-Diverse Persons (PURPOSE 2 phase 3 trial) nej.md/4fFWVzJ #IDTwitter
VIEWPOINTS | As naloxone formulations have increased in number and availability over the years, so, too, has the strength of the data demonstrating naloxone’s efficacy and effectiveness in treating acute opioid overdose in clinical and real-world settings. ow.ly/PGmQ50TYe3v
Often asked about glucagon like peptide receptor 1 agonists GLP-1RA as interventions for persons with psychiatric illness targeting weight and metabolic. Here is a state of the art summary of the field today. doi.org/10.1017/S10928…
Atypical antipsychotics worked better than traditional mood stabilizers when treating youth with acute mania or mixed episodes of bipolar disorder. ow.ly/IMIo50U2zsg
🧵RFK Jr. is an antivax, AIDS-denying, absolutely antiscientific conspiracist.🧵 ANTIVAX: “They get [vaccinated], that night they have a fever of 103, they go to sleep, and three months later their brain is gone... This is a Holocaust, what this is doing to our country.” /1
![tylerblack32's tweet image. 🧵RFK Jr. is an antivax, AIDS-denying, absolutely antiscientific conspiracist.🧵
ANTIVAX:
“They get [vaccinated], that night they have a fever of 103, they go to sleep, and three months later their brain is gone... This is a Holocaust, what this is doing to our country.”
/1](https://pbs.twimg.com/media/GdKhMWTWYAAhEe9.jpg)
AUTHORS' OWN WORDS: "Six months after an #opioidoverdose #naloxonedistribution #OEND training, emergency responders #EMS attitudes toward people who overdose & their risk compensation beliefs remained improved." #lawenforcement =negative attitudes/beliefs vs EMS.…
According to dynamical systems, psychiatric disorders can be seen as energy landscapes with peaks and valleys. OCD has deep valleys where neural activity gets stuck, while schizophrenia has shallow valleys that let neural activity roam too freely, connecting unrelated ideas.
Racial divide in large study. Compared to Whites... > #Schizophrenia: Black/Hispanic given older antipsychotics, less atypicals/clozapine > #Depression/#Bipolar: Black/Hispanic/Asian given more antipsychotics, less lamotrigine/antidepressants pubmed.ncbi.nlm.nih.gov/38671009 #psychiatry
An increase in amygdala reactivity was associated with risk of relapse after antidepressant discontinuation and may represent a functional neuroimaging marker that could inform clinical decisions around antidepressant discontinuation. ja.ma/4elvQjQ
One of the many great lessons taught to me by @AllenFrancesMD is to be skeptical of experts in particular psychiatric disorders. Given their intellectual (and sometimes financial) commitments, they almost always tend to overestimate the prevalence of their favorite diagnoses.
1 in 24 people develop elevated calcium on #lithium therapy, usually due to hyperparathyroidism. Check calcium regularly, and if it is high check PTH. If that is elevated, refer to consult (may treat with cinacalcet). From new review pubmed.ncbi.nlm.nih.gov/39192574 #bipolar #depression
Interesting effects of GLP 1 receptor agonists (e.g.semaglutide) on functional connectivity in the brain; Implications for potential application in mental disorders treatment and prevention Congrats to the team. pubmed.ncbi.nlm.nih.gov/39515485/
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