@Sathi_W Profile picture

Sathi Wijeyesinghe

@Sathi_W

Pediatrician scientist | PGY-2 @BCM_pediatrics | MD/PhD from @UMNMSTP and @Masopust_Vezys lab | former postbac @NIH VRC | Terp alum @UofMaryland

Joined June 2019
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Sathi Wijeyesinghe Reposted

Hear from a talented lineup of immunologists next Wednesday, Sept 18 featuring @zurisullivan, @alexwellsies, @DjenetBousbaine, @ValeriaMReyes, @CicaCanesso, @ScientistBecs, @Liwen_Deng811, & @NZanluqui Register: bit.ly/ScrippsLeaders

Immuno_Mike's tweet image. Hear from a talented lineup of immunologists next Wednesday, Sept 18 featuring @zurisullivan, @alexwellsies, @DjenetBousbaine, @ValeriaMReyes, @CicaCanesso, @ScientistBecs, @Liwen_Deng811, & @NZanluqui.

Register: <a style="text-decoration: none;" rel="nofollow" target="_blank" href="https://t.co/hsdYAY6N0r">bit.ly/ScrippsLeaders</a>

Sathi Wijeyesinghe Reposted

Our paper describing in vitro resident memory T cell differentiation in an epithelial organoid model is out at @CellReports doi.org/10.1016/j.celr…. If you are excited about T cells and reproductive mucosa, we are looking for postdocs-apply.interfolio.com/145385


Sathi Wijeyesinghe Reposted

Excited to share our perspective on resident memory T cells in solid tumors!!Huge thanks to @ImmunityCP and @Jodi___G Amazing figures and artwork from @KatarinaECheng and support from the whole @Masopust_Vezys team. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…


Sathi Wijeyesinghe Reposted

Delighted to share our new work @Jamequistlab @CFI_UMN on cytokine regulation of homeostatic memory CD8 T cells biorxiv.org/content/10.110… tl;dr homeostatic circulating and resident memory CD8 T cells are resilient to loss of IL-7Rα (surprise!) Please RT Thread follows

Collaboration between IL-7 and IL-15 enables adaptation of tissue-resident and circulating memory CD8+ T cells biorxiv.org/cgi/content/sh… #biorxiv_immuno



Sathi Wijeyesinghe Reposted

We are seeking 1-2 talented immunology students to join our team in the tropical and picturesque region of North Queensland, where summers are endless and sunshine is abundant.

RolandRuscher's tweet image. We are seeking 1-2 talented immunology students to join our team in the tropical and picturesque region of North Queensland, where summers are endless and sunshine is abundant.

Great postdoc opportunity with @BeuraLab #AAI2024

Sathi_W's tweet image. Great postdoc opportunity with @BeuraLab. #AAI2024

Sathi Wijeyesinghe Reposted

Cutting Edge: First Lung Infection Permanently Enlarges Lymph Nodes and Enhances New T Cell Responses journals.aai.org/jimmunol/artic…


Sathi Wijeyesinghe Reposted

The Thompson lab is officially live! Excited to announce that I recently accepted a faculty position @JohnsHopkinsMMI studying immunometabolic regulation of vaccine responses. Kicking off the new lab with my first purchase, obviously a @CytekBio flow cytometer!

E_A_Thompson's tweet image. The Thompson lab is officially live! Excited to announce that I recently accepted a faculty position @JohnsHopkinsMMI studying immunometabolic regulation of vaccine responses. Kicking off the new lab with my first purchase, obviously a @CytekBio flow cytometer!

Sathi Wijeyesinghe Reposted

Very excited to share our paper led by @madisonstrine Intestinal tuft cell immune privilege enables norovirus persistence | Science Immunology science.org/doi/10.1126/sc… 1/n


Sathi Wijeyesinghe Reposted

CD39 is expressed on functional effector and tissue resident memory CD8+ T cells biorxiv.org/cgi/content/sh… #biorxiv_immuno


Sathi Wijeyesinghe Reposted

Thrilled to announce the opening of the Srivatsan Lab (srivatsan-lab.com) at the @fredhutch The lab will be building new sequencing technologies to understand how our cells and bodies form over the course of development.

The newest @FredHutch Basic Sciences lab opens its doors! The @SRsrivatsan Lab is developing new sequencing technologies to interrogate structure-function relationships during vertebrate development. The lab is growing and hiring at all levels: srivatsan-lab.com



Sathi Wijeyesinghe Reposted

Michael is the godfather of viral pathogenesis and the reason so many labs have been able to use LCMV (and other viruses) for fundamental discoveries. He was an inspiration and giant in the field. I will be forever grateful to the advice he gave me early in my career. RIP MBAO

The Scripps Research community mourns the passing of Michael Oldstone, MD, esteemed virologist and professor emeritus, who helped establish the viral pathogenesis field and shaped our understanding of host immune responses scripps.edu/news-and-event…

scrippsresearch's tweet image. The Scripps Research community mourns the passing of Michael Oldstone, MD, esteemed virologist and professor emeritus, who helped establish the viral pathogenesis field and shaped our understanding of host immune responses <a style="text-decoration: none;" rel="nofollow" target="_blank" href="https://t.co/v21IUqSVii">scripps.edu/news-and-event…</a>


Sathi Wijeyesinghe Reposted

Our study on human T cell memory formation during infancy and childhood revealing progressive maturation of tissue resident subsets in mucosal sites is online—thanks to @tconnors22, @_shivaliv and great collaborators @AYatesGroup, @psimslab @bruskolab cell.com/immunity/fullt…


Sathi Wijeyesinghe Reposted

Very excited to share our work in @SciImmunology on the migration properties of CD8+ tumor-infiltrating lymphocytes (TILs)! Using 🐭 models and parabiosis, we uncovered unique features of tumor-resident T cells. Spoiler 🚨tumor ≠ healthy tissue. science.org/doi/10.1126/sc… 1/7


Sathi Wijeyesinghe Reposted

Tissue resident memory T cells trigger rapid exudation and local antibody accumulation Local immunity is more than IgA. It is also the establishment of local tissue resident memory T cells (Trm). mucosalimmunology.org/article/S1933-…


Sathi Wijeyesinghe Reposted

check out our paper from my time as a postdoc in @Masopust_Vezys lab! cellular and humoral immunity working together🤝! Resident memory T cells induce rapid (within hrs) vascular permeability in the female reproductive tract, enabling infiltration of neutralizing antibodies 1/5

Work from @PCRosato1,@Masopust_Vezys, and colleagues show CD8+ TRMs may enhance local #humoral immunity. mucosalimmunology.org/article/S1933-…

MucosalImmunol's tweet image. Work from @PCRosato1,@Masopust_Vezys, and colleagues show CD8+ TRMs may enhance local #humoral immunity. <a style="text-decoration: none;" rel="nofollow" target="_blank" href="https://t.co/QhiyYE0piB">mucosalimmunology.org/article/S1933-…</a>


Sathi Wijeyesinghe Reposted

Authored by Andrew G. Soerens et al, we show that #Tcells are capable of proliferating in response to iterative stimulation for over 10yrs! And produce enough progeny to occupy a volume 30,000x the Earth's volume! @Nature nature.com/articles/s4158…


Sathi Wijeyesinghe Reposted

Very excited to share our work on HIV, out this week in @Nature We sort and RNA-seq infected cells solely based on the detection of provirus DNA. Infected CD4 T cells have unique signatures that help to explain HIV persistence in vivo. nature.com/articles/s4158…


Sathi Wijeyesinghe Reposted

Exciting news! @UCDavis is hiring 100 new faculty! Inviting friends @NSBE @SACNAS @SHPE @NationalMANRRS @AAHHEorg & more! @Chancellor_May says that bringing diverse researchers and scholars together can help us solve society’s greatest challenges! ucdavis.edu/academics/facu…


Sathi Wijeyesinghe Reposted

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