Muhammad saleem khan
@Saleem5353KhanPostdoc at #Shanghai Public Health Clinical Center, Fudan & Dalian University/ #PhD #Zhejiang University. #Phages research
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9th French Phage Network meeting next week in Sète! See program here: site.phages.fr/explorer-resso…
.@AntaniJo (@Yale) etal developed a microscopy-based technique to measure #phage attachment to bacterial cells. This method provides an alternative to the century-old Phage Adsorption Assay. Feel free to reach out with any questions: jyot.antani@yale.edu buff.ly/4fd1PnD
Here is a video that summaries the key findings! Once again, special thanks to my wonderful mentor @JunLiuLab at @YaleMed @YaleMicroPath Lots more discoveries to come at @McGillMed @McGill_ACB @CRBSMcGill !
Happy and proud to see this paper online! We resolved the in-situ architecture of the P. aeruginosa Type IV pilus machine and discovered the localisation and role of PilY1. Great collaboration with @JunLiuLab @Dr_Lori_Burrows @BrunLabCaulo @PLynneHowell . nature.com/articles/s4146…
Prediction of strain level phage–host interactions across the Escherichia genus using only genomic information | Nature Microbiology nature.com/articles/s4156…
.@NIAIDNews has announced a $6M funding opportunity to establish Centers for Accelerating #PhageTherapy to combat ESKAPE pathogens. By this time next year, 2-3 phage therapy centers in the US will be funded. Deadline: Jan 28, 2025 Reach out to: Kyung Moon buff.ly/3C37jme
Happy to share my first PhD manuscript. I combined structure-based domain identification, #alphafold, and clustering methods to build a phage tail fiber structure Atlas. I also used #cryoEM to confirm the structure of five #phage fibers.
🚨 New preprint alert! 🚨 We're excited to share our latest work: "Towards a complete phage tail fiber structure atlas" 🦠🔬 of first author @VKleinSousa We developed #RBPseg for segmenting and merging phage tail fibers using structural prediction tools. tinyurl.com/58cn2ew7
I am excited to announce several post-doc positions studying gene regulation and cell biology of spirochetes are available in the @NIH Biology of Spirochetes Unit, opening 2025 in Bethesda, MD @NIAIDNews! Join our team and work on the dynamic NIH campus: training.nih.gov/jobs/pdfi-0128…
This is great! @NIAIDNews have launched a collection of public domain illustrations (currently 550 individual icons) bioart.niaid.nih.gov
The CPT's Phage Naming Service is now available at phns.phagetech.org! This service lets you quickly check if a phage name already exists in either NCBI or PhagesDB.
1/ 🧵 Thrilled to share work of @EligoBio just published in @Nature ! We show proof of principle results of efficient base editing performed on E. coli directly in the mouse gut 🦠💡 #Microbiome #SyntheticBiology nature.com/articles/s4158…
Researchers at Paris-based @EligoBio have engineered a phage-derived vector to deliver a base editor and modify E. coli while they are colonizing the mouse gut. Learn more: ow.ly/8k4l50Sz81a
Pseudomonas aeruginosa faces a fitness trade-off between mucosal colonization and antibiotic tolerance during airway infection | Nature Microbiology nature.com/articles/s4156…
My laboratory at UVA is seeking postdocs and technicians to study membrane protein signaling in bacterial-phage conflict. Please forward if you know someone who would be interested! Job postings linked below: jobs.virginia.edu/us/en/job/UOVU… jobs.virginia.edu/us/en/job/UOVU…
I am excited to share our latest publication looking at the effect of bacteriophage transplantation from wild into captive mice. #microbiome #phpageome doi.org/10.1093/ismejo… First, comparison of wild and captive phageomes and bacteriomes revealed that (1/5)
Oh, that one... hurts. I guess it is a good sign that we are getting totally scooped by the best of the best. But ouch.
We discovered a new immune signaling molecule: N7-cADPR N7-cADPR is produced by phage-stimulated TIR proteins. It activates a bacterial caspase, which then degrades essential proteins to curb infection Preprint: biorxiv.org/cgi/content/sh… Congrats @FrancoisRousset & @IlyaOsterman
Well said @Phage_UniFAHS! We are late with our posting as we attended the webinar organized by our colleagues from @PhageEU
#WorldPhageDay is celebrating nature's powerful defenders: #Phages! By targeting harmful bacteria (e.g. Salmonella, E. coli, Listeria, or Vibrio), these tiny heroes protect our food, animals, and environment. From farm to fork, they combat #AMR & safeguard the food value chains.
#WorldPhageWeek2024 linkedin.com/posts/marcrese… (Central image created with Dall.E 3)
Did you know that today, October 22nd, is World Phage Day? This day also marks the beginning of World Phage Week (October 22nd-28th), dedicated to raising awareness about the life-saving potential of #bacteriophages. #WorldPhageDay #WorldPhageWeek #PhageTherapy
How are phages cleared from the bloodstream? We learned that serum factors but not neutrophils help clear phages. Thanks to Rob McBride and our terrific team of collaborators. insight.jci.org/articles/view/…
Happy to share the final version of our work at @PLOSBiology👇 journals.plos.org/plosbiology/ar… Thank you to all the reviewers, and a big shoutout to first author @simrankushwaha 👏
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