Melvin Noé González
@MNoeGonzalezHusband. Father. Postdoc at @UCPH_health studying transcription| Alumni @ScienceStowers @lcgunam | 🇲🇽 Jarocho de corazón, biochemist by training
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Finally, my most meaningful contribution to this world. Bienvenido, Rafa!
Extremely happy to share our new work on a transcription checkpoint at the beginning of genes. Congratulations to Dan Blears and Jiangman Lou for their impressive work on this. eur02.safelinks.protection.outlook.com/?url=https%3A%…
We (@SvejstrupLab) are back on Biorxiv, this time with an exciting work from @davidlopmar Check it out!!
Really excited to share my preprint describing a novel activation mechanism of CDK12/13 by the PAF1 complex essential for transcription elongation! biorxiv.org/content/10.110…
🔥Hot from the press: Our new publication in @ScienceMagazine about #oxidative #stress and how it mediates #metabolic decline via the #ribotoxic stress response kinase #ZAKα! science.org/doi/10.1126/sc… #MAPK #metabolism #translation #NASH #aging #obesity @UCPH_Research @UCPH_health
I fully endorse this message. At @ScienceStowers, you really can have it all.
Support, connection, & #coffee – just three of the reasons that @stowersgrad alumn @MNoeGonzalez says you should choose our #PhD in #Biology program. Learn more + apply here: bit.ly/44VM6DI #GradSchool #GraduateSchool
Really excited to be attending my first CSHL conference on the mechanism of eukaryotic transcription! If you’re interested on double digits CDKs (CDK12) or believe in life after CDK9, come see me on Thursday evening at my poster # 194 #moet2023
How do cells minimize the threats to genome stability from transcription? Our work identifies a new complex, assembled by SOSS and INTAC, as a key player in maintaining genome stability by attenuating R-loop levels.
Nature research paper: R-loop dependent promoter-proximal termination ensures genome stability go.nature.com/47o5lYU
Paper alert! 🐣🐣❤️So happy to see this published @NatureSMB Congratulations to Andrés, @AndyPuig, Sherlyn @SherlynClaudio and all authors. Well done Andrés! @IFC_UNAM Thanks to @sarakosman, @DimitrisTypas and reviewers. nature.com/articles/s4159…
Checkout our new preprint!!!👇👇 Outstanding piece by Andres Penagos @AndyPuig, Sherlyn Claudio @SherlynClaudio, Aura Stephenson, et al. Thank you Andres for all your hard work and congratulations to all authors involved! 🥳biorxiv.org/content/10.110… (thread)
The end of epigenetics? 😂 "Pol II machinery may not require epigenetic marks to resume transcription on the newly synthesized DNA" nature.com/articles/s4158…
Why does Integrator-PP2A (INTAC), the dominant player in promoter-proximal Pol II termination, harbor two enzymatic activities, and how do they differ in gene expression control? Our latest work 👇provides an answer.
Online Now: INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II dlvr.it/Sml3jr
The world´s wealthiest foundation, Novo Nordisk Foundation, will stop funding for one of the best research centers in Denmark and the world- the Center for Protein Research. A sad day for Danish Science. There must be better ways to do new things, without dismantling the best.
Big news from the lab!
I very much look forward to serving as the new vice-president for Life Sciences of the ERC, a fantastic organisation, which has transformed European science. erc.europa.eu/news-events/ne…
Massive news: eLife to abolish accept/reject decisions: papers will just be “peer reviewed”. Others can argue about this, but lots of interesting consequences. 1/9 elifesciences.org/articles/83889
Impactful words by @CarolynBertozzi today on how diversity in her trainees enabled creativity, not playing by the rules, and ultimately the work that built the field of bioorthogonal chemistry. Diverse science leads to better science!
The @ERC_Research Vice-president of Life Sciences is looking for a Senior Admin!
Looking for an exciting job in Science Admin? Look no further! nature.com/naturecareers/…
Really heartbreaking news. Incredibly tragic ending to what would otherwise been future scientific leaders originating from latinoamérica. I can't imagine the loss felt by their friends, colleagues, and parents.
Excited to finally share our discovery of ACTMAP – the missing factor for mature actin biosynthesis @ScienceMagazine science.org/doi/10.1126/sc… #actin #cytoskeleton #ScienceResearch Tweetorial below 👇 1/9
A new preprint from the @durocherlab lab has dropped! In this work, we map genes that suppress induction of DNA damage in human cells 🧵: biorxiv.org/content/10.110… . .
Everyone working on Integrator and Restrictor after #EMBOrna3primeEnds
Getting back to lab after a four day conference and telling everyone how it went twitter.com/mineralpurveyo…
In Oxford for #EMBOrna3primeEnds? @SvejstrupLab is presenting several projects during the meeting! Jesper is talking tomorrow and postdocs David (Tue) and Melvin (Wed) have posters Come talk to us if interested in transcriptional CDKs, Integrator, RNAPII CTD or termination!
Trains breaking down in both Copenhagen and London and a 90 minute (!!!) waiting time through heathrow immigration but finally on the bus to #EMBOrna3primeEnds. First conference as a postdoc! 🤩
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