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@DocAnnaMEcuriosityBEATSfear - ALLpostsMYown - DenkerKeinDichter#BIOMOLECULARSTASIS #INTERACTOME #drugdiscovery #proteases #MOA #biologicalAGING #andDisease #ubiquitous
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Why to leave academia? Once you are out of the Lab, people forget you and the efforts and project steering and impactful contribution to the project- what a waste of time and money - this was a learning for life- thank you for the personal development ;) pubmed.ncbi.nlm.nih.gov/37620860/?utm_…
We’re hiring a postdoc! babrahaminstitute.livevacancies.co.uk/#/job/details/… Really cool starting point for this project (ubiquitin/proteostasis/ageing/yeast—contact me!), with the chance to tap into the know-how of super proteostasis labs next door (@DellaDavid_Lab @Ian_J_McGough @FloreyLab @t_rayon). 1/2
New work from the lab @NatureAging! 🌱🌱 We asked whether the ability of plants to suppress pathological protein aggregation can be applied into human cell and animal models to delay or even prevent neurodegenerative diseases nature.com/articles/s4358…
I’ve been doing this for a while now and N-end rule degradation continues to amaze me 🤯 jbc.org/article/S0021-…
For the first time, scientists have analysed the connectome for part of the brain in the common octopus that’s involved in acquiring long-term memories. elifesciences.org/articles/84257…
Technical and biological replicates are different things - a technical replicate sharpens your estimation of a sample mean; a biological replicate controls for biological variability. And independent experiments are something different to either. 👇 totalinternalreflectionblog.com/2017/09/06/see…
Reminder from @cshlmeetings to be yourself and thrive where you are planted! #cshlubiq
☕️NEW: @FrydmanLab @EmSontagMU @FaboPolanco & co show that nuclear & juxtanuclear misfolded proteins converge to opposite nuclear envelope sides, proximal to nuclear–vacuolar junctions for ESCRT-dependent egress to the vacuole. rdcu.be/daDh5 nature.com/articles/s4155…
PhD position in Lipid Cell Biology / Functional Membrane Plasticity @HolthuisL The Holthuis Lab at Osnabrück University is looking for a PhD student to work on PLASTICITY & PHYSIOLOGICAL RELEVANCE OF ORGANELLAR LIPID CODES jobrxiv.org/job/osnabruck-…">jobrxiv.org/job/osnabruck-… ... jobrxiv.org/job/osnabruck-…">jobrxiv.org/job/osnabruck-…
Salad spinners are the best plate centrifuges.
We are hiring @fischerlab1! Multiple roles, with wonderful @kdonovan1008 at Dana-Farber Cancer Institute @DFCI_ChemBio Great entry into TPD and E3 ligase space and what a team to work with!
Happy 2023! If you are interested in getting involved in the TPD/Chem Bio space, @fischerlab1 is looking for someone organized and enthusiastic to work with me on various projects. Role includes admin and wet lab work. Please RT careers.dana-farber.org/job/senior-res…
Please RT! 📢I am looking for a PhD student📢 interested in Chemical Biology, #RNA, #Fluorophores, #Imaging & developing new technologies for spatial biology @UniHeidelberg @IPMB_HD in my group. Please apply! More info: sunbulgroup.com/phd-wanted
This is just about the best thing I’ve read all year. How delightful the Twitter algorithm brought it to me and my morning coffee time on Christmas. The state of the literature in my own field (medicinal chemistry) can confirm peer review isn’t working, and may never work.
Science ran a big experiment on itself for the last ~60 years. It didn't work out. experimentalhistory.substack.com/p/the-rise-and…
Congratulations to Kara L Schneider &Per Widlund and the team for nice piece of work. ..happy I could support the research in “Using reporters of different misfolded proteins reveals differential strategies in processing protein aggregates - ScienceDirect” sciencedirect.com/science/articl…
The @FrydmanLab solved the long-standing puzzle of whether the mRNA (CAG repeats) or the protein (polyQ stretch) causes proteotoxicity in Huntington’s disease. Ribosome collision 💥 is the key! Brilliant. Must read!!! biorxiv.org/content/10.110…
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