@ClydeFrancks Profile picture

Clyde Francks

@ClydeFrancks

Prof. of Brain Imaging Genomics @ Max Planck Institute & Donders Institute, Netherlands. Biologist interested in genes, brains, behaviour, left-right asymmetry

Joined August 2014
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Pinned

Is genetic disposition to #dyslexia associated with brain structure? @neurosoren investigated in over 30,000 adults using data from @uk_biobank & @23andMeResearch , highlighting brain networks involved in motor, language and vision functions medrxiv.org/content/10.110… 1/8 ⬇️

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Clyde Francks Reposted

Excited to see our work featured in Trends in Cognitive Sciences! Huge congratulations to the team! @Valerie_Pu @ClydeFrancks

Out now in Trends in Cognitive Sciences: a short article on studying brain asymmetry in terms of global patterns across the entire brain cell.com/trends/cogniti… Led by @xiangzhenkong and Yi Pu at Zhejiang Uni, with some contributions from myself



Out now in Trends in Cognitive Sciences: a short article on studying brain asymmetry in terms of global patterns across the entire brain cell.com/trends/cogniti… Led by @xiangzhenkong and Yi Pu at Zhejiang Uni, with some contributions from myself


It was nice to learn how flies 🪰🪰 can help understand some aspects of human hyperactivity, through being on the PhD exam committee of @benharich , student of @annette_schenck @BFranke_lab @_MariekeKlein_ . Congratulations Dr. Harich and supervisors!!


Clyde Francks Reposted

So, for now, I'm staying. I hope others will too. We can't, as scientists, just spend our time talking to each other. The stakes are just too high to cede the battleground of ideas, tempting as it may be. 6/6


Pre-adolescent Brain Asymmetry: Developmental Trajectory, Cognitive and Psychiatric Effects, Neurobiological and Environmental Influences in ABCD Study researchsquare.com/article/rs-525…


Individualized cortical thickness asymmetry in Autism Spectrum Disorders and Schizophrenia medrxiv.org/content/10.110…


Want to do a PhD in Nijmegen on 'Mapping language-relevant genetic effects on brain variability using normative modelling' with myself, @amarquand and @ProfSimonFisher ? Applications welcome via mpi.nl/imprs-phd-fell… 🧠🧬


Clyde Francks Reposted

New paper! This paper shows the use of normative models for understanding the effects of rare genetic variants on brain organisation at the level of the individual. nature.com/articles/s4422… Great stuff from @CFraza!


Clyde Francks Reposted

So excited about this study led by @Annel3illoT and NiharikaJhingan: Good news for us, aging folks -- some 🧠 networks (e.g., the language one!) don't seem to deteriorate with age! Long live the language network!

[NEW PREPRINT!] The language network ages well biorxiv.org/cgi/content/sh… Co-led with Niharika Jhingan, in collaboration with @ev_fedorenko, @AphasiaLab, @MVarkanitsa, @raryksin, & Idan Blank. 🧵 Details 👇



Clyde Francks Reposted

HOW DOES YOUR GENETIC CODE affect your brain? 💡A new genetic roadmap of the brain (in today's Nature Genetics) reports: 💡100s of genomic loci affect deep brain structures 💡Genetic variants driving brain volume overlap with risk loci for Parkinson's, ADHD, many brain diseases…

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Clyde Francks Reposted

A 1,000,000th reminder the crucial importance of basic research. Ambros and Ruvkun were looking into understanding nematode genetics and development, not looking for a drug, and ended up opening an entire new area in biology


Clyde Francks Reposted

The left/right logical/holistic idea is 1% true, 99% hype. The two hemispheres do have some different functions, but it's not as simple as logical/holistic.


Clyde Francks Reposted

Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness. New paper by @jsamelink & al. @Genes_Speak @ProfSimonFisher @ClydeFrancks doi.org/10.1038/s42003…


First paper from the PhD of @jsamelink on the genetics of functional connectivity between regions of the brain important for language nature.com/articles/s4200… many congratulations Jitse!! @MPI_NL @DondersInst


Clyde Francks Reposted

Dissecting the Reduced Penetrance of Putative Loss-of-Function Variants in Population-Scale Biobanks medrxiv.org/cgi/content/sh… #medRxiv


Assortative mating across nine psychiatric disorders is consistent and persistent over cultures and generations medrxiv.org/content/10.110…


Clyde Francks Reposted

Ever wondered about #hemisphericAsymmetries in #Borderline personality disorder? We've got you covered! Check out our new systematic review in @SpringerNature ⬇️📖: link.springer.com/article/10.100… With @ocklenBLOG and co! 🧠👩‍🔬 #Psychiatry #Laterality


Substantial role of rare inherited variation in individuals with developmental disorders medrxiv.org/content/10.110…


Clyde Francks Reposted

We are accepting applications again to our fantastic fully funded program with excellent faculty and interdisciplinary research opportunities! APPLY NOW!!! cognition.maxplanckschools.org/en/application #maxplanckschools #passionforscience 👌💪🏻🧠🍀

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New study led by @xiangzhenkong used machine learning to investigate brain structural asymmetry and its associations with cognitive functions, aging, and aging-related diseases biorxiv.org/content/10.110… @PTenigma


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