Chris Goss, DO
@ChrisGossDOInternal medicine PGY-3. Aspiring nephrologist. Brazilian jiu-jitsu.
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Did you know that to induce contrast nepphropathy in rats, in addition to a load of contrast you also have to give them an NSAID and block natural vasodilation with a nitric oxide inhibitor?
Horacio Adrogué is going hard that his formula is right and the data showing that it doesn't work is from people holding it wrong #KidneyWk
✅ FURST formula for calculating fluid restriction for correction of hyponatremia #Nephpearls 👉🏼 ncbi.nlm.nih.gov/m/pubmed/25995…
Fact #1: In the "average" patient, a dose of 100 mg iv furosemide is safer than 1 liter iv crystalloids Fact #2: In every patient, a dose of 100 mg iv furosemide is ALWAYS safer than 1 liter iv crystalloids
Causes and Effects of Hyperhydration and Dehydration #medtwitter #foamed #meded #medicine
#Sepsis associated acute kidney injury can occur in the absence of overt signs of hypoperfusion and hemodynamic instability. 👇Microcirculatory and inflammatory alterations in sepsis-associated #AKI 🔗sciencedirect.com/science/articl… Click 'ALT' for figure description #Nephpearls #MedEd
We need to have more goals of care discussions with our patients
Should you give albumin with loop diuretics to augment diuresis? I've been asked this three different times today so a quick🧵of my thoughts #nephtwitter #MedTwitter @MedTweetorials
What causes anemia in CKD ?? ALL OF THESE !! 1. ⬇️EPO production 2. Blood loss during dialysis 3. Nutritional deficiencies 4. BM fibrosis (2°hyperparathyroidism) 5. ⬇️RBC lifespan #MedTwitter plz add more !! @divyaa24 @thisis_drgsp @nainamdar
ACE inhibitors and ARBs are not “nephrotoxins.” They improve renal blood flow. But they reduce GFR, and impair potassium elimination. Which is why we might hold them in [severe and/or worsening] AKI.
Core Curriculum by @JamesNovakNeph and @dhekidney: Pharmacology and therapeutic use of diuretics in states of volume overload and strategies to overcome diuretic resistance bit.ly/3BTbVYb (FREE)
Updates on treatment of type 2 diabetic mellitus with CKD by Prof Lim Soo Kun. Other than renoprotection, SGLT2 inhibitor has effects on other organs as well. #ISNWCN @ISNWCN @ISNkidneycare
Another amazing whiteboard teaching session from @ubcpharmacy student Stephanie Xue!
CKD disproportionately affects those of minoritized race and ethnicity. This Perspective describes the transition from the clinical use of eGFR with the race variable to reporting eGFR without race at @UWNephrology bit.ly/KID0006522021 @NNkinsi
You know how trimethoprim-sulfamethoxazole can cause hyperkalemia? And remember triamterene, the potassium-sparing diuretic that acts on the ENaC channel?
Intercalated cells response to Metabolic Alkalosis and Metabolic Acidosis
Do you ever wonder how come vasoconstrictors revert renal vasoconstriction in #hepatorenal syndrome? Found it counterintuitive? Here is a 30 sec animation:
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