Anila
@AnilaCaraNephrology Resident, Glomerular Disease Fellow @GlomCon class ‘22-‘23, Kidney Pathology Certificate Program fellow @GlomCon
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🚨 Dear all, do not miss this new KDIGO webinar series on NephroGenetics 🧬 ! Please do not hesitate to share, including amongst our younger colleagues @ERAkidney @com_SFNDT @FiliereORKiD @CJNephro @ynptweets @SNINephrologie
Join us for "Hiding in Plain Sight: The Utility of Genetic Testing in Common Forms of CKD," the next module in KDIGO's new webinar series on implementing genetic testing for CKD. Wednesday, December 4, at 3:00 PM EST. Register: kdigo.co/Module-2-Genet… In this CME webinar,…
Dr. @fervenzafernan1 educating us on new treatment strategies in IgA nephropathy; & reminding us that just like proteinuria, hematuria is a good marker of disease activity and should be included in evaluating patient outcomes! 💯 @ASNKidney #KidneyWk ✨
Time for a new look at how to manage LN. The old proteinuric centric approach is not enough. In patients with anti-ds-DNA and proliferative LN, targeting immunological remission (negative anti-ds-DNA and normalization of complement) is the key 🔑! kidney-international.org/article/S0085-…
Membranous Nephropathy (MN): It is becoming increasingly important to identify the antigen in MN. Each MN-antigen has distinctive clinical, pathology, and prognostic implications. Mass spectrometry is the method of choice for identifying MN antigens. academic.oup.com/ckj/article/do…
Our new study is out! By STED microscopy on kidney biopsy and ELISA assays we show 1/3 of pediatric and half of adult patients (more in primary FSGS) have autoantibodies against slit antigens different from nephrin. i.e. anti-slit Abs kidney-international.org/action/showPdf…
Can’t skip this session with Dr Caz @Tiff_Caza @GlomCon
Join GlomCon this Sunday: Updates in Membranous Nephropathy by Dr. Tiffany Caza ID: 875 5077 1266 Passcode 202122 sign up 👉🏻 bit.ly/3zm4tYy #GlomCon
Belimumab followed by Rituximab in #SLE #Lupus phase 3 RCT No difference in BEL/PBO vs BEL/RTX [@Lupus Forum] #Rheumatology #MedTwitter
Study demonstrates polycystin-2 is a key regulator of cardiomyocyte’s ability to produce natriuretic peptides in mouse and human models and that loss of cardiac-specific polycystin-2 in the absence of kidney involvement results in elevated diastolic and systolic BP…
In remembrance of Barry Morton Brenner, MD (1937-2024) Joseph V. Bonventre and Giuseppe Remuzzi @BWHKidney @MarioNegriIRCCS doi.org/10.1016/j.kint…
Light Chain MGUS Calculator #Onconephrology 🦀 #Nephpearls H/T @SabineKaram6 👉🏼 istopmm.com/lcmgus/ 👉🏼 pubmed.ncbi.nlm.nih.gov/36100605/
In four patients with severe autoimmune disease, teclistimab, a bispecific antibody to B-cell maturation antigen and CD3, resulted in autoantibody reduction and clinical response after short-term follow-up. Read the full correspondence: nej.md/3AZzWA8
🚨Travere Therapeutics Announces Full FDA Approval of FILSPARI® (sparsentan) for IgA Nephropathy ir.travere.com/news-releases/…
A woman with aggressive refractory systemic lupus erythematosus was treated with a short course of the bispecific antibody teclistamab (anti–B-cell maturation antigen and anti-CD3) and had a drug-free complete remission. Full correspondence: nej.md/3Th6ewX
Genetics of chronic kidney disease @NEJM nej.md/3SMFpAv @AfricanAFRAN @ISNeducation @ISNkidneycare @ERAkidney @WHO @WHOAFRO
The patient is a 70 years old male who presents with a creatinine of 5 mg/dl and a history of primary myelofibrosis. The biopsy shows a kidney with severe glomerular and tubulointerstitial chronicity, approaching end-stage kidney disease from arterionephrosclerosis.…
1/n pt w/CKD (unknown etiology) arrives to clinic for follow up. Baseline Cr 1.7-2.1, past 🚬, base UPCR 0.4. Two months prior to the visit, Cr had ⬆️ to 4.2 and PCP stopped ARB. New labs: Cr down to 2.5. ARB was resumed at 50% reduced dose. 2 mo later, new visit: Cr back ⬆️ 3.8
Now online in @NDTsocial Anti-C1Q monitoring predicts relapses of #lupus nephritis 🧐High titres of anti-C1qAb at start of therapy and their persistent positivity at 1 year is strongly associated with renal flares. ▶️academic.oup.com/ndt/article-ab…
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